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Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado

2013, Number 3

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Rev Esp Med Quir 2013; 18 (3)

Subclinical thyroid Dysfunction in Adults Evaluated at the Laboratory of a Third Level Unit

Beraud RLF, Ramos ZA, Sahagún FJE

Language: Spanish
References: 28
Page: 235-240
PDF size: 321.21 Kb.


ABSTRACT

Background: Subclinical thyroid dysfunction is more common than overt dysfunction; however, its prevalence is significantly different from one region to another, even in the same country.
Objective: To determine the prevalence of subclinical thyroid dysfunction in evaluated adults in the clinical laboratory of a tertiary care unit.
Material and method: A descriptive and retrospective study was done including data from individuals aged 18 years or older, assessed by measuring thyrotropic hormone (TSH) and free thyroxine (fT4), from February to June 2011, in the clinical laboratory of Regional Hospital Valentin Gómez Farías, Jalisco, Mexico. Data were classified according to functional status, gender, and age groups (younger and older adults). Statistical analysis was performed with the χ2 test.
Results: Data from 2,091 individuals were analyzed: 506 old adults (68.59 ± 7.89 years) and 1,585 young adults (44.15 ± 9.84 years). Prevalence of subclinical hypothyroidism was 8.8%: men 7.1%, women 9.2% (p = 0.173); old adults 11.1%, young adults 8% (p = 0.034). Prevalence of subclinical hyperthyroidism was 11.1%: women 12.7%, men 5% (p ‹ 0.001); young adults 10.6%, old adults 12.6% (p = 0.201).
Conclusions: Subclinical thyroid dysfunction was found in one fifth of evaluated individuals and it is more frequent than overt dysfunction, about 4:1. It is advisable to conduct a study with a representative sample to generalize results.


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