2005, Number 6
<< Back Next >>
Acta Ortop Mex 2005; 19 (6)
Application of bone marrow autologous in delay of consolidation and post-traumatic pseudoarthrosis
Reyna OG, Soto JI, Regalado CR
Language: Spanish
References: 15
Page: 248-251
PDF size: 76.00 Kb.
ABSTRACT
The use of bone marrow as graft autologous bases on the capacity of potentiality that have the cells hematopoietics fresh, that, after being grafted, stimulate the formation of new cells of the woven host. The intention of our work was to evaluate the efficacy of to apply bone marrow autologous in cases of delay of consolidation and postraumatic pseudoarthrosis. Material and methods. The study was pilot and blind, in 16 patients diagnosed as delay of consolidation or postraumatic pseudoarthrosis, treated by means of application of bone marrow autologous for percutaneous route. Results. The surgical time of the capture and application of bone marrow was in average of 40 minutes. Thirteen patients evolved to consolidation grade the III in maximum 24 weeks and three did not present X-ray information of consolidation. Conclusions. The results were satisfactory. We consider that the use of percutaneous bone marrow applied in form to stimulate the osteogenesis in case of pseudoarthrosis has advantages. It is a simple skill that does not present complications as break of the donating place or infection, and it is of low cost.
REFERENCES
Consejo C, Ripalda P, Forriol F: Reparación de un defecto de mandíbula. Estudio experimental macroscópico en ovejas. Patología del Aparato Locomotor 2004; 2(2): 105-113.
Connolly JF, Guse R, Tieddeman J, et al: Autologous marrow injection as a substitute for operative grafting of tibial nonunions. Clinic Orthop 1991; 266: 259-269.
Connolly JF: Injectable bone marrow preparations to stimulate osteogenic repair. Clinic Orthop 1995; 313: 8-18.
Garg NK, Gaur S: Percutaneous autogenous bone-marrow grafting in congenital pseudoarthrosis. J Bone Joint Surg (Br) 1995; 776-B: 830-831.
Healey JH, Zimmerman PA, McDonnell JM et al: Percutaneous bone marrow grafting of delayed union and nonunion in cancer patients. Clinic Orthop 1990; 281: 280-285.
Kelly CM, Wilkins RM, Gitelis S et al: The use of a surgical grade calcium sulfate as a bone graft substitute. Clinic Orthop 2001; 382: 42-50.
Linares GL, Rico MG: Trasplante de médula ósea autóloga. Experiencia en el tratamiento de lesiones de origen tumoral y seudotumoral para estimulación de neoformación ósea. Rev Mex Ortop Traum 1998; 12(5): 437-440.
Lokiec F, Ezra E, Khermosh O et al. Simple bone cysts treated by percutaneous autologous marrow grafting: a preliminary report. J Bone Joint Surg (Br) 1996; 78-B: 934-937.
Rougraff BT, Kling TJ: Treatment of active unicameral bone cyst with percutaneous injection of demineralized bone matrix and autogenous bone marrow. J Bone Joint Surg (Am) 2002; 84-A: 921-929.
Tiedeman JJ, Connolly JF, Strates BS et al: Treatment of nonunion by percutaneous injection of bone marrow and demineralized bone matrix. An experimental study in dogs. Clinic Orthop 1991; 268: 294-302.
Troum S, Dalton M: Osteogenesis in a rat model: Use of bone marrow cells and biodegradable gelatin matrix carrier. J South Orthop Assoc 2001; 10(1): 37-43.
Colchero RF, Olvera BJ: La consolidación de las fracturas. Su fisiología y otros datos de importancia. Revista Médica IMSS 1982; 21(4): 374-381.
Burwell RG: The function of bone marrow in the incorporation of a bone graft. Clin Orthop 1985; 200: 125-141.
Raffi SH, Lyden D: Therapeutic stem and progenitor cell transplantation for organize vascularization and regeneration. Nat Med 2003; 9(6): 702-712.
Weber BG, Cech O, Amaya S y cols: Seudoartrosis, y fisiopatología, biomecánica, tratamiento, resultados. Editorial científico médica, Barcelona, España 1986.