Rector RN, Guerrero ÁF, de la Garza RMA, Cabral RC, Oliver PR, Téllez JH

Language: Spanish
References: 0
Page: 919-926
PDF size: 163.41 Kb.

ABSTRACT

Objective: determine the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of the clindamycin gel for clinical use in periodontitis. Introduction: currently, the main goal of periodontal treatment is to stop the progression of periodontitis. The scaling and root planing in conjunction with local therapy have shown satisfactory results. In cases where periodontal therapy respond poorly or refractory site, the use of antibiotics are a good choice. In contrast to systemic antimicrobial therapy, local therapy remains high concentrations of antibiotic with a short range and limited, thus decreasing the adverse effects among other benefits. Materials and methods: this study was conducted on the premises of the Faculty of Dentistry Universidad Autónoma de Tamaulipas and Integral Dental Unit & Specialties Center for Research and Development in Health Sciences (CIDCS) of the Universidad Autónoma de Nuevo Leon, which assess the bacteriostatic and bactericidal efficacy of clindamycin gel, on 4 of the microorganisms in periodontitis (Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Prevotella intermedia and Forsythia Tanerella). By means of MIC and MBC, and to assess the stability of the gel for storage. Results: in relation to the values of the bacteriostatic and bactericidal efficacy after application of Clindamycin gel, it showed a significant reduction in the activity of the bacterial colonies, which translates to a clinical feasibility of the drug. Conclusions: significantly decreased significantly the activity of bacterial colonies with the application of Clindamycin gel. Clindamycin gel proved to be an effective drug in response to the microbiota studied. The clinical management of Clindamycin gel, it is considered that can be used easily without causing patient discomfort and local injury. The use of Clindamycin gel showed no adverse reactions to study bacterial colonies. Clindamycin gel is a topical drug which may be helping in the immediate postoperative periodontal.