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2013, Number 4

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Rev Mex Patol Clin Med Lab 2013; 60 (4)

Cerebrospinal fluid variables in central nervous system infections

González SY, Sánchez FP, Mediaceja VO

Language: Spanish
References: 27
Page: 252-258
PDF size: 158.05 Kb.


ABSTRACT

Meningitis is a syndrome that can be clinically fulminating or self-limiting and etiologically can be caused by multiple infectious agents. The sudden onset of symptoms and a fatal outcome in a few hours or the permanence of serious neurological sequelae condition the large social impact of these diseases. We performed a descriptive, observational case series, in a sample of 171 patients with infection in the central nervous system (CNS) at discharge from Hospital «Dr. Gustavo Aldereguía Lima» during the period from January 2000 to December 2006, in order to determine the cytochemical characteristics of the cerebrospinal fluid (CSF) in these patients. Higher incidence infections were viral meningitis and meningitis bacterial, which accounted for 97% being the viral meningitis at ages 15-30 year-old male, while the meningitis bacterial resulted more frequent in female patients aged between 46-64 years. CSF cytochemical features found in viral meningitis were transparent and moderate lymphocytic pleocytosis, CSF glycorrhachia/glucose ratio › 0.60, while in the meningitis bacterial neutrophilic pleocytosis predominated between 200 and 900 cells/mm3, CSF glycorrhachia/glucose ratio of 0.22 and turbid aspect. The results turn out to be close to those reported in the literature, being of great importance for better differential diagnosis of CNS infections that affect us.


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