Bravo-Cañón M, Ventura-Bravo ZA

Language: Spanish
References: 17
Page: 154-163
PDF size: 508.65 Kb.

ABSTRACT

Purpose. Establish a magnetic resonance (MR) protocol at CT Scanner de Mexico to determine multifocality and multicentricity in patients with non-metastatic breast cancer.
Method. A prospective study conducted from March 2010 through December 2011 in the CT Scanner de Mexico MR area. Patients who presented lesions suspected of malignancy in mammograms and ultrasound studies, patients with neoadjuvant treatment for breast cancer, and patients with BIRADS 6 were evaluated. The purpose was to identify secondary foci: multifocal (in the same quadrant), multicentric (in different quadrants), and localized in the contralateral breast or more than 5 centimeters from the primary focus.
Results. The results showed occult foci not detected by mammogram or ultrasound, and in one case bilaterality.
Conclusion. MR can identify foci of secondary cancer which may not be routinely removed in surgery; also, it helps advise patients on management and treatment to follow based on the results.

REFERENCES

1. Coombs N, Boyages J. Multifocal and multicentric breast cancer. Does each focus matter? J Clin Oncol 2005;23:7497- 7502.

2. Berg W. Gilbreath P. Multicentric and Multifocal Cancer. Wholes Breast Us in preoperative evaluation. Radiology 2000;214:59-66.

3. Kaplan J. Dershaw D. Resonancia magnética después del tratamiento. En RM de Mama. Morris y Liberman (ed). Madrid: Marban 2010:207-215.

4. SERAM y ACR. Breast Imaging and Reporting Data System. Ed. 2006.

5. La Londe L, David J, Trop I. Magnetic resonance imaging in breast cancer. Eur J Surg Oncol 2006;32:901-910.

6. Gibbs P, Liney GP, Lowry M, Kneeshaw PJ, Turnbull LW. Differentiation of benign and malignant sub 1cm breast lesiones using dynamic contrast enhanced MRI. Breast 2004;13:115-121.

7. Eeles R, Knee G, Mangion J. Ebbs J. Multicentric breast cancer: clonality and prognostic studies. Breast Cancer Rest. Treat. Springer 2010.

8. Newstead GM. MR imaging in the managment of patients with breast cancer. Semin Ultrasound CT MR 2006;27(4):320-332.

9. Al Hallaq, et al. Magnetic Resonance Imaging identifies multifocal and multicentric disease in breast cancer patients whoa re eligible for paril breast irradiation. Am Cancer Society 2008;113(9):2408-2414.

10. Wilkinson L, Given-Wilson R, Hall T, Potts H, Sharma A, Smith E. Increasing the diagnosis of multifocal primary breast cancer by the use of bilateral whole-breast ultrasound. Clin Radiol 2005;60:573-578.

11. Uchida K, Yamashita A, Kawase K, Kamiya K. Screening ultrasonography revealed 15% of mammographically occult breast cancers. Breast Cancer 2008.

12. Buchberger W, Niehoff A, Obrist P, DeKoekkoek-Doll P, Dunser M. Clinically and mammographically occult breast lesions: detection and classification with high resolution sonography. Semin Ultrasound CT MR 2000;21(4):325-336.

13. Majid AS, de Paredes ES, Doherty RD, Sharma NR, Salvador X. Missed breast carcinoma: pitfalls and pearls. Radiographics 2003;23(4):881-895.

14. Maza M, García L. Utilización de resonancia magnética en el estudio de la patología mamaria. Diagnóstico por imagen. En Tecnología Radiológica 2005;57:12-15.

15. Heywang SH, Hahn D, Schmidt H, et al. MR imaging of breat using Gd- DTPA. J Comput Assit Tomogr 1986;10:19-204.

16. Balu-Maestra C, Chapellier C, Bleusa A, et al. Imaging in evaluation of response to neoadjuvant breast cancer treatment benefits of MRI. Breast Cancer Rest Treat 2002;72:145-152.

17. Abraham DC, Jones RC, Jones SE, et al. Evaluation of neoadjuvant chemotherapeutic response of locally advanced breast cancer by magnetic resonance imaging. Cancer 1996;78:91-100.