2013, Number 1
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Rev Mex Neuroci 2013; 14 (1)
Congenital malformations associated with misoprostol use: Report of two cases
Sánchez-Rodríguez G, Luévanos-Gurrola K, Ramírez-Cázares AC, Rodríguez-Bonito R, Rodríguez-Balderrama I
Language: Spanish
References: 12
Page: 50-53
PDF size: 215.74 Kb.
ABSTRACT
The use of misoprostol is contraindicated in pregnancy
because of its potential as an abortifacient and its
relationship with malformations such as microcephaly,
Möbius syndrome and clubfoot, among other
complications. We present two cases of patients with
malformations evident at term birth with a history of
misoprostol intake by the mother in the first trimester. The
use of misoprostol in countries where abortion is illegal
increases its misuse with the consequent appearance of
newborns with various congenital malformations. It is
important to disseminate and understand the teratogenic
effects of this drug, as well as the control of its use.
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