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ISSN 1995-9494 (Electronic)
Revista del Hospital Clínico Quirúrgico "Arnaldo Milián Castro"

2013, Number 3

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Acta Med Cent 2013; 7 (3)

Bowen’s disease

Rodríguez MJR, de Armas REL

Language: Spanish
References: 29
Page:
PDF size: 359.76 Kb.


ABSTRACT

Bowen's disease is a squamous cell carcinoma (in situ) in which there are dysplastic changes throughout the thickness of the affected epidermis. It generally affects light skinned people over 60 years of age. Clinically, it is characterized by papules and solitary or multiple plaques, that are erythematous-scaly and with slow centrifugal growth. The differential diagnosis must be established with chronic dermatoses, psoriasis, chronic eczema, superficial basal cell carcinoma and cutaneous Paget's disease. Only 5% of cases progress to invasive squamous cell carcinoma. The treatment of choice for Bowen's disease is surgery; other alternatives are topical chemotherapy with 5-fluorouracil and imiquimod, cryosurgery and, more recently, photodynamic therapy.


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