2013, Number 3
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Perinatol Reprod Hum 2013; 27 (3)
Epidemiology of twin pregnancy at the Instituto Nacional de Perinatología Isidro Espinosa de los Reyes
Delgado-Becerra A, Morales-Barquet DA
Language: Spanish
References: 26
Page: 153-160
PDF size: 253.81 Kb.
ABSTRACT
Introduction: The twin pregnancy is considered a high risk entity. In our institution, the percentage of live newborns due to double pregnancies varies between 4.8 and 6.5%. Multiple pregnancies have a greater impact on health systems due to high rate of complications.
Objective: To describe the maternal and neonatal characteristics of twin pregnancies at the Instituto Nacional de Perinatología, and determine differences in morbidity between the first and second twin.
Material and Methods: The study was conducted in the all newborns products of twin pregnancies from January 1
st 2007 to December 31
st 2008 were included. Descriptive statistics by means of tables and analytical statistics was used to compare the twins.
Results: A total of 654 newborn cases from 327 twin pregnancies were included. Spontaneous pregnancy was found in 92%. Preeclampsia was the most common cause of maternal mortality presented in 14.2% of the pregnancies. Intrauterine growth restriction was found in 55.2% and prematurity in 54.9%. No statistical differences were observed in the morbidity between the first and the second twin.
Conclusions: Due to an increased maternal and fetal morbidity and mortality observed in twin pregnancies, measures to prevent complications most be applied during the perinatal period.
REFERENCES
Endres L, Wilkins I. Epidemiology and biology of multiple gestations. Clin Perinatol. 2005; 32: 301-14.
Ahued J. Prematurez, un enfoque perinatal. México: Editores de Textos Mexicanos; 2004.
Luke B. The changing pattern of multiple births in the United States: maternal and infant characteristics, 1973 and 1990. Obstet Gynecol. 1994; 84: 101-6.
Blondel B, Kogan MD, Alexander GR, Dattani N, Kramer MS, Macfarlane A et al. The impact of the increasing number of multiple births on the rates of preterm birth and low birth weight: an international study. Am J Public Health. 2002; 92: 1323-30.
Collins J. Global epidemiology of multiple birth. Reprod Biomed Online. 2007; 3: 45-52.
Blondel B, Kaminski M. Trends in the occurrence, determinants, and consequences of multiple births. Semin Perinatol. 2002; 26: 239-49.
Cameron AH, Edwards JH, Derom R, Thiery M, Boelaert R. The value of twin surveys in the study of malformations. Eur J Obstet Gynecol Reprod Biol. 1983; 14: 347-56.
Cunnigham FG, Gant NF, Leveno KJ et al. Williams Obstetrics. 20th ed. Stanford: Appleton y Lange; 1997.
Refuerzo JS, Momirova V, Peaceman AM, Sciscione A, Rouse DJ, Caritis SN et al. Neonatal outcomes in twin pregnancies delivered moderately preterm, late preterm, and term. Am J Perinatol. 2010; 27: 537-42.
Briceño PC, Briceño SL. Embarazo gemelar en el Hospital Chiquinquirá de Maracaibo. Rev Obstet Ginecol Venez. 2004; 64: 3-14.
Torres-Torres C, Pérez-Borbón G, Benavides-Serralde JA, Guzmán-Huerta ME, Hernández-Andrade E. Prevalencia y complicaciones del embarazo gemelar monocorial biamniótico. Ginecol Obstet Mex. 2010; 78: 181-6.
Departamento de Análisis y Estadística, Instituto Nacional de Perinatología. “Dr. Isidro Espinosa de los Reyes”.
Alexander GR, Kogan M, Martin J, Papiernik E. What are the fetal growth patterns of singletons, twins, and triplets in the United States? Clin Obstet Gynecol. 1998; 41: 114-25.
Cleary-Goldman J, D’Alton ME. Growth abnormalities and multiple gestations. Semin Perinatol. 2008; 32: 206-12.
Dodd JM, Crowther CA. Specialized antenatal clinics for women with a multiple pregnancy for improving maternal and infant outcomes. Cochrane Database Syst Rev. 2012; 8: CD005300.
Schinzel AA, Smith DW, Miller JR. Monozygotic twinning and structural defects. J Pediatr. 1979; 95: 921-30.
Hofmeyr GJ, Barrett JF, Crowther CA. Planned caesarean section for women with a twin pregnancy. Cochrane Database Syst Rev. 2011; 7: CD006553.
Pijnenborg JM, Oei SG. The monoamniotic twin: a riskful event. Eur J Obstet Gynecol Reprod Biol. 1999; 86: 51-3.
Monset-Couchard M, de Bethmann O, Relier JP. Long term outcome of small versus appropiate size for gestational age co-twins/triplets. Arch Dis Child Fetal Neonatal Ed. 2004; 89: F310-4.
Branum AM, Schoendorf KC. The effect of birth weight discordance on twin neonatal mortality. Obstet Gynecol. 2003; 101: 570-4.
Shinwell ES, Blickstein I, Lusky A, Reichman B. Effect of birth order on neonatal morbidity and mortality among very low birthweight twins: a population based study. Arch Dis Child Fetal Neonatal Ed. 2004; 89: F145-F8.
Wen SW, Fung KF, Huang L, Demissie K, Joseph KS, Allen AC et al. Fetal and neonatal mortality among twin gestations in Canadian population: the effect of intrapair birthweight discordance. Am J Perinatol. 2005; 22: 279-86.
Jones KL. Smith’s recognizable patterns of human malformation. 6th ed. Oxford: Elsevier Saunders; 2006.
Fernández CL, Cruz MM, Ortigosa CE, Peñuela OM. Estudio comparativo del crecimiento y desarrollo entre parejas de gemelos al año de edad egresados de Unidades de Cuidado Intensivo e Intermedio Neonatal. Bol Med Hosp Infant Mex. 1996; 53: 159-67.
Armson BA, O’Connell C, Persad V, Joseph KS, Young DC, Baskett TF. Determinants of Perinatal Mortality and serious neonatal morbidity in the second twin. Obstet Gynecol. 2006; 108: 556-64.
Rossi AC, Mullin PM, Chmait RH. Neonatal outcomes of twins according to birth order, presentation and mode of delivery: a systematic review and meta-analysis. BJOG. 2011; 118: 523-32.