Partida-Medina LR, Hernández-Cruz EM

Language: Spanish
References: 18
Page: 212-217
PDF size: 41.33 Kb.

ABSTRACT

Recent reports show the association between the endothelial function and migraine, as well as of possible endothelial dysfunction with ischemic cerebrovascular disease, coronary artery disease and other systemic vascular pathologies. Several studies disclose the possible dysfunction of the endothelial cells in migraine involving the vascular wall, vascular tone control, endothelial depending hemostasia, and genetic disorders in nitric oxide synthesis. Other studies have demonstrated that the vasodilatory response in reactive hyperemia tests is decrease in patients with migraine when compared with non-migraine subjects. In this review, we describe the different abnormalities that have been found in endothelial function in patients with migraine. It appears that migraine has a direct effect on blood vessels, that is, a neurovascular phenomenon. Otherwise, blood vessels have an effect on migraine producing a neurovascular condition. The relationship of the blood vessels with Migraine raises the pathophysiologic hypothesis of a Hemo-neural and/or Neuro-vascular origin, concluding at the time, the two are inextricably.

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