Varela HA, Vega BS, Silva AS, Mosquera BG

Language: Spanish
References: 26
Page: 135-141
PDF size: 72.18 Kb.

ABSTRACT

Introduction: Neuroblastic Migration Disorders constitute a group of malformations of cortical development. During the last decades, there have been advances in molecular biology, genetics and imaging techniques for its diagnosis but not so for its treatment. These elements, together with the development of a Neurologic Restoration Program at our Center, compelled us to perform the following study. Objective: To clinically characterize the hospitalized patients at our center with an imagenologic diagnosis of neuroblastic migration disorders and to evaluate the effects of our Neurologic Restoration Program. Patients and Methods: We performed a series of studies on the 114 patients in pediatric ages who underwent the Neurologic Restoration Program, affected with Neuroblastic Migration disorders. The neurologic sequels were evaluated before and after the Program through Gross Motor Functions, Articulatory Praxis and Ashworth Spasticity Scales. Results: 35 cases with heterotopies, 24 with complex Agiria-paquigiria, 28 with squizencenphalia, 21 with polymicrogiria and 6 with hemimegalencephalia were diagnosed. After the application of the program we obtained an improvement of 7.9% in the Gross Motor Function scale, a 9.6% in Articulatory Praxis Scale and a diminishing of 0.6 points in the Ashworth Spasticity Scale. Conclusions: Clinic characteristics of our patients do not differ from those referred in other series. After the application of the program, benefits were obtained, a fact demonstrated with a significant statistical improvement in the three applied scales.

REFERENCES

1. Heros CH, Morcos JJ. Cerebrovascular Surg: Past, Present, and Future. Neurosurg. 2000; 47(5): 1007-33.

2. Kassel FN, Torner JC, Haley C, Jane JA, Adams HP, Kongable GL. The International Cooperative study on the timing of Aneurysm surg. J Neurosurg. 1990; 73: 18-36.

3. Tateshima S, Murayama Y, Gobin PY, Duckwiler RG, Guglielmi G, Viñuela F. Endovascular treatment of basilar tip aneurysms using Guglielmi detachable coils: Anatomic and clinical outcomes in 73 patients from a single institution. Neurosurg. 2000; 47 (6): 1332-42.

4. Malek MA, Halbach W, Phatouras CC, Lampert ET, Meyers MP, Dowd FCh. Balloon-assist technique for endovascular coil embolization of geometrically difficult intracranial aneurysms. Neurosurg. 2000; 46: 1397-1408.

5. Shanno BG, Armonda AR, Benítez BR, Rosenwasser HR. Assessment of acutely unsuccessful attempts at detachable cloling in intracranial aneurysm. Neurosurg. 2001; 48(5): 1066-74.

6. Levy E, Koebbe JCh, Horowitz BM, Jungreis ACh, Pride LG, Dutton K, Kassam A, Purdy DPh. Rupture of intracranial aneurysms during endovascular coiling: Management and outcomes. Neurosurg. 2001; 49(4): 807-13.

7. Tummala PR, Chu MR, Madison TM, Meyers M, Tubman D, Nussbaum SE. Outcome after aneurysm rupture during endovascular coil embolization. Neurosurg. 2001; 49(5): 1059-67.

8. Tanapura Ch, Kato Y, Sano H, Varghese SM, Idesawa Y, Hayashi J, Kanno T. Treatment of severe subarachnoid hemorrhage-440 cases: Cliping versus coiling. Pan Arab J Neurosurg. 2004; 8(2): 28-32.

9. Varela HA , Mendoza RE, Vega BS, Medrano GR, Silva AS, Montejo MJ, Peñones MR. Manejo clínico de la hemorragia subaracnoidea aneurismática (Monografía). 2005. Disponible en: www.cmw.sld.cu/ inter_pag.php?pagina=publicaciones

10. Pareda-Cardentey AI, Falero-Pérez AR. Hemorragia Subaracnoidea. Rev Neurol. 2002; 34(10): 954-66.

11. Gans K, Nieuwkamp JD, Rimkel EJG, Algra A. Timing of aneurysm surg in subarachnoid hemorrhage: A systematic review of the literature. Neurosurg. 2002; 50(2): 336-42.

12. Chung YR, Carter SB, Norbach A, Budzik R, Putnam Ch, Ogilvy SCh. Management outcomes for ruptured and unruptured aneurysms in the elderly. Neurosurg. 2000; 47(4): 827-33.

13. Vega BSD, Silva AS, Mosquera BG, Varela HA. La cirugía de los aneurismas intracraneanos en la séptima y octava décadas de la vida. Neurocirugía 2002; 13: 371-77.

14. Zipfel JG, Dacey GR. Update on the management of unruptured intracranial aneurysm. Neurosurg Focus. 2004; 17(5).

15. Hpriuchi T, Tanaka Y, Hongo K. Surgical treatment for Aneurysmal Subarachnoid Hemorrhage in the 8th and 9th decades of life. Neurosurg. 2005; 56: 469-75.

16. Vega BS, Silva AS, Peñones MR. Aneurismas intracraneales múltiples en Camaguey, Cuba. Rev Neurol. 2003; 37(2): 1112-17.

17. Varela HA. Cirugía Aneurismática. Análisis de resultados. Tesis de Terminación de Residencia. Instituto Superior de Ciencias Médicas “Carlos J Finaly”, Camagüey, Cuba. 1998.

18. López RJR. Aneurismas intracraneales: Aspectos clínicos y quirúrgicos. Experiencia en 41 pacientes. Tesis de Terminación de Residencia. Hospital Militar “Dr. Carlos J Finlay”. Ciudad de La Habana. 1998.

19. Forget RTh, Benítez R, Veznedaroglu E, Sharan A, Mitchell W, Silva M, et al. A review of size and location of ruptured intracranial aneurysms. Neurosurg. 2001; 49(6): 1322-26.

20. Day LA, Morcos JJ, Revilla F. Management of aneurysms of the anterior circulation. In: YOUMANS. Neurological Surg. PHILADELPHIA: Sounders. 1996: 1272-1309.

21. Renganchary SS, Wilkins HR. Neurosurgical Operative Atlas. 1997.

22. Rhoton LA. Aneurysms. Neurosurg. 2002; 51 (suppl 1): 121-58.

23. Leipzing J Th, Morgan J, Horner GT, Payner T, Redelman K, Johnson SC. Analysis of intraoperative rupture in the surgical treatment of 1694 sacular aneurysms. Neurosurg. 2005; 56: 455-68.

24. Naso BW, Rhea HA, Poole A. Managememt and outcome in a low-volume cerebral aneurysm practice. Neurosurg. 2001; 48(1): 91-100.

25. Vega BSD, Gutiérrez MFG. La enseñanza de la neurocirugía vascular. Rev Mex Neuroci. 2004; 5(5): 441-47.

26. Vega BSD, Gutiérrez MFG. Evaluación del método de enseñanza práctica de la neurocirugía vascular. Rev Mex Neuroci. 2004; 5(6): 554-58.