2013, Number 2
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Rev Cub Med Mil 2013; 42 (2)
Risk factors and severity of diabetic retinopathy
Castro CK, López DN, Rodríguez RD, Suárez PJC, Llerena RJA
Language: Spanish
References: 19
Page: 181-190
PDF size: 84.10 Kb.
ABSTRACT
Objective: to characterize patients diagnosed with diabetic retinopathy in relation to
severity and presence of risk factors.
Methods: an observational, descriptive and cross-sectional study was conducted in
135 patients who had been diagnosed as having diabetic retinopathy in the
Ophthalmology Department of Dr. Luis Díaz Soto Central Military Hospital.
Results: there was a predominance of non-proliferative diabetic retinopathy; more
patients were classified as Type 2 diabetics; the most used form of treatment was
insulin therapy; the 33,3 % with more than 31 years of diagnosis of Diabetes Mellitus
and a deficient glycemic control in a 54,1 %; urinary albumin excretion less than
20mg/L (normal). In the group with mild and moderate non-proliferative diabetic
retinopathy, the largest number of patients presented with a period of evolution of the
disease between 6 and 10 years, with oral hypoglycaemic therapy, good glycemic
control and urinary albumin excretion of less than 20 mg/L. In the group with severe
non-proliferative diabetic retinopathy and proliferative diabetic retinopathy
predominated: time of diagnosis of the disease of more than 21 years, insulin
treatment, deficient glycemic control and urinary albumin excretion greater than 100
mg/L.
Conclusions: most patients were characterized by presenting mild non-proliferative
diabetic retinopathy, being Type 2 diabetics, receiving insulin therapy, with evolution
of diabetes for more than 21 years, and having deficient glycemic control and normal
urinary albumin excretion.
REFERENCES
King H, Aubert R, Herman H. Global burden of diabetes 1995-2050: prevalence, numerical estimates and projections. Diabetes Care. 1997;21:1414-37.
Cairols M, Castillo J, González-Juanatey JR, Mostaza JM, PomarJL. Enfermedad arterial asintomática. Rev Clin Esp. 2003;203(Suppl 3):1-57.
Fernández Vigo J. Diabetes ocular. Barcelona: EDIKA-Med. 1992. p. 375.
Friedman SM, Rubin ML. Diabetic retinopathy: newer therapies to prevent blindness. Geriatrics. 1992:47:71-81.
Kanski Jack J, Thomas Dafydd J. El ojo en las enfermedades sistémicas. 2ª ed. Philadelphia: Marbán; 1992. p. 19-25.
Cervera Taulet E, Díaz-Llopis M, Udaondo P, Torralba C. Antiangiogénicos y retinopatía diabética. Av Diabetol. 2008;24(1):21-6.
Wilkinson CP, Ferris FL, Klein RE, Lee PP, Agardh CD, Davis M, et al. Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales. Ophthalmology. 2003;110:1677-82.
Kowluru RA. Effect of advanced glycation end products on accelerated opoptosis of retinal capillary cells under in vitro conditions. Life Sci. 2005;76:1051-60.
Frank RN. Diabetic Retinopathy. N Engl J Med. 2004;350:48-58.
Teruel Maicas C, Fernandez Real JM, Ricart W , Valent Ferrer R , Valles Prats M . Prevalencia de retinopatía diabética en la población de diabéticos diagnosticados en las Comarcas de Girona. Estudios de los factores asociados. Arch Soc Esp Oftalmol [Internet] 2005 [citado 16 de Feb 2012];(80)2. Disponible en: http://scielo.isciii.es/scielo.php?pid=S0365-66912005000200006&script=sci_arttext
Licea Puig ME , Maciquez Rodríguez E, Cruz Hernández J. Factores de riesgo asociados con la aparición de la retinopatía diabética. Rev Cubana Endocrinol [Internet] 2007 [citado 16 de Feb 2012];(18)3. Disponible en: http://scielo.sld.cu/scielo.php?pid=S0864- 21762006000200007&script=sci_arttext&tlng=es
Molina Martín JC, Hernández Silva Y, Molina Martín LA. Factores de riesgos asociados a retinopatía diabética. Rev Cubana Oftalmol [Internet] 2006 [citado 16 de Feb de 2012];(19)2. Disponible en: http://scielo.sld.cu/scielo.php?pid=S0864- 21762006000200007&script=sci_arttext&tlng=es
Esteban M, Rodríguez F, Jiménez J, Bueno A. Prevalencia de retinopatía en diabéticos de más de 10 años de evolución en la zona norte de Granada. Arch Soc Esp Oftalmol. 1999;3:1-7.
Janghorbani M, Amini M, Ghanbari H, Safaiee H. Incidence of and risk factors for diabetic retinopathy in Isfahan, Iran. Ophthalmic Epidemiol. 2003;10(2):81-95.
The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long term complications in insulin-dependent diabetes mellitus. N Engl J Med. 1993;329:977-86.
UK Prospective Diabetes Study Group. Intensive blood glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes. Lancet. 1998;352:837-53.
UK Prospective diabetes study (UKPDS) group. Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes. Br Med J. 1998;317:703-18.
Licea ME, Perich PA, Cabrera-Rode E, Figueredo E. Excreción urinaria de albúmina en grupo de personas con diabetes mellitus tipo 2. Av Diabetol. 2001;17:203-13.
Figueroa V, Urroz KM, Arguedas C. Importancia clínica de la proteinuria en diabetes mellitus. Acta Med Costarric. 2001;43:1-9.