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2012, Number 99

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Rev Enfer Infec Pediatr 2012; 25.26 (99)

Bacterial meningitis: microbiological behavior in the past 21 years in a third level pediatric hospital

Coria LJJ, Balderrabano SNA, Rosales URE, Juárez EM, Díaz CT

Language: Spanish
References: 19
Page: 101-108
PDF size: 234.68 Kb.


ABSTRACT

Despite advances in the treatment of bacterial meningitis (BM), it remains a major public health problem, since it goes against the patient’s life, especially in developing countries. Objective: To evaluate the epidemiological changes of the BM in terms of microbiology in the last 21 years in children older than one month admitted to the Hospital Infantil de Mexico Federico Gomez. Material and Methods: We reviewed 424 medical records of patients of both sexes from 0 to 18 years old, admitted to the hospital in the last 21 years with a diagnosis of BM, which had the following criteria: 1) cerebrospinal fluid (CSF) with pleocytosis › 10 cells/mm3 and a positive CSF culture or latex agglutination for H. influenzae type b (Hib), S. pneumoniae (S. pn) or Neisseria meningitidis (NMN), or Gram stain positive in CSF and blood culture positive for Hib or S. pn bacteria NMN. 2) positive culture for any agent other than the usual. Results: From the total, only 300 patients showed changes in CSF with a germ isolated in 83 cases, Hib remains the most important infectious agent followed by S. pn, with 46 (55.42%) and 15 (18.7%) isolates, respectively. The age group most affected was › 3 months to 2 years. Conclusions: In the last 21 years (1989-2010), the incidence of BM as well as associated mortality have declined significantly, however, shows the involvement of other infectious agents.


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