medigraphic.com
ISSN 1025-0255 (Electronic)

2013, Number 2

<< Back Next >>

AMC 2013; 17 (2)

Characterization of adenomatoid odontogenic tumor in a Colombian population

Duque SFL, Castillón PL, Ardila MCM

Language: Spanish
References: 32
Page: 188-200
PDF size: 203.08 Kb.


ABSTRACT

Background: adenomatoid odontogenic tumor is the most common benign epithelial neoplasia derived from the odontogenic epithelium that appears in the maxilla.
Objective: to describe adenomatoid odontogenic tumors observed in patients for 20 years at the Stomatology and Maxillofacial Surgery Unit of the San Vicente de Paul University Hospital and at the Dentistry Faculty of the Antioquia University.
Method: a retrospective study was conducted with patients diagnosed with adenomatoid odontogenic tumors confirmed by means of histopathology. Some variables like age, gender, and frequency and characteristics of the adenomatoid odontogenic tumors were analyzed.
Results: seven patients with an adenomatoid odontogenic tumor were observed. All the tumors were intraosseous (central); 71.5 % of them were follicular and 28.5 % were extrafollicular. The tumors were more frequently placed in the jaw. Women were more affected than men with a ratio of 2.5:1. The peak incidence was found in the second decade of life. All the lesions were located in the front area of the maxilla. Lateral incisor teeth were more frequently associated to follicular adenomatoid odontogenic tumor (60 %). Most of the patients showed facial asymmetry, no symptoms, and a progress longer than six months.
Conclusions: the distribution and characteristics of the adenomatoid odontogenic tumors of the studied population are similar to those found in other populations. Nevertheless, the present research showed more cases related to lateral incisor teeth in young patients.


REFERENCES

  1. Lucas RB. Pathology of tumors of the oral tissues. 4ºEd. Edinburgh: Churchill Livingstone; 1984.

  2. Philipsen HP, Reichart PA, Siar CH, Ng KH, Lau SH, Zhang X, et al. An updated clinical and epidemiological profile of the adenomatoide odontogenic tumour: a collaborative retrospective study. J Oral Pathol Med. 2007;36:383-93.

  3. Stafne EC. Epithelial tumours associated with developmental cysts of the maxilla. A report of three cases. Oral Surg Oral Med Oral Pathol. 1948;1:887-90.

  4. Philipsen HP, Birn H. The adenomatoid odontogenic tumours. Ameloblastic adenomatoid tumour or adenoameloblastom. Acta Pathol Microbiol Scand. 1969;75:375-9.

  5. Kramer I, Pindborg J, Shear M. Histological typing of odontogenic tumors. OMS. Cancer. 1992;70:2988-94.

  6. Barnes L, Eveson JW, Reichart P, Sidransky D. Eds. Pathology & Genetics. Head and Neck. Geneva: World Health Organization; 2005.

  7. Vasudevan K, Kumar S, Vijayasamundeeswari, Vigneswari S. Adenomatoid odontogenic tumor, an uncommon tumor. Contemp Clin Dent. 2012;3(2):245-7.

  8. Prakash AR, Reddy PS; Rajanikanth, Bavle RM. Concomitant occurrence of cemento-ossifying fibroma and adenomatoid odontogenic tumor with bilateral impacted permanent canines in the mandible. Indian J Dent Res. 2012;23(3):434-5.

  9. Krishna A, Kaveri H, Naveen Kumar RK, Kumaraswamy KL, Shylaja S, Murthy S. Overexpression of MDM2 protein in ameloblastomas as compared to adenomatoid odontogenic tumor. J Cancer Res Ther. 2012;8(2):232-7.

  10. Becker T, Buchner A, Kaffe I. Critical evaluation of the radiological and clinical features of adenomatoid odontogenic tumour. Dentomaxillofac Radiol. 2012;41(7):533-40.

  11. Philipsen HP, Reichart PA, Zhang KH, Nikai H, Yu QX. Adenomatoid odontogenic tumor: biologic profile based on 499 cases. J Oral Pathol Med. 1991;20:149-58.

  12. Tsuneki M, Maruyama S, Yamazaki M, Cheng J, Saku T Podoplanin expression profiles characteristic of odontogenic tumor-specific tissue architectures. Pathol Res Pract. 2012;208(3):140-6.

  13. Kumar H, Vandana R, Kumar G. Immunohistochemical expression of cyclin D1 in ameloblastomas and adenomatoid odontogenic tumors. J Oral Maxillofac Pathol. 2011;15(3):283-7.

  14. Crivelini MM, Felipini RC, Miyahara GI, de Sousa SC. Expression of odontogenic ameloblast-associated protein, amelotin, ameloblastin, and amelogenin in odontogenic tumors: immunohistochemical analysis and pathogenetic considerations. J Oral Pathol Med. 2012;41(3):272-80.

  15. John JB, John RR. Adenomatoid odontogenic tumor associated with dentigerous cyst in posterior maxilla: A case report and review of literature. J Oral Maxillofac Pathol. 2010;14(2):59-62.

  16. Salehinejad J, Zare-Mahmoodabadi R, Saghafi S, Jafarian AH, Ghazi N, Rajaei AR, et al. Immunohistochemical detection of p53 and PCNA in ameloblastoma and adenomatoid odontogenic tumor. J Oral Sci. 2011;53(2):213-7.

  17. Ide F, Mishima K, Kikuchi K, Horie N, Yamachika S, Satomura K, et al. Development and growth of adenomatoid odontogenic tumor related to formation and eruption of teeth. Head Neck Pathol. 2011;5(2):123-32.

  18. Saghravanian N, Jafarzadeh H, Bashardoost N, Pahlavan N, Shirinbak I. Odontogenic tumors in an Iranian population: a 30-year evaluation. J Oral Sci. 2010;52(3):391-6.

  19. Ide F. Inter-radicular adenomatoid odontogenic tumor of the anterior mandible. J Oral Maxillofac Surg. 2010;68(2):490-1.

  20. de Matos FR, Nonaka CF, Pinto LP, de Souza LB, de Almeida Freitas R. Adenomatoid odontogenic tumor: retrospective study of 15 cases with emphasis on histopathologic features. Head Neck Pathol. 2012;6(4):430-7.

  21. Swasdison S, Dhanuthai K, Jainkittivong A, Philipsen HP. Adenomatoid odontogenic tumors: an analysis of 67 cases in a Thai population. Oral Surg Oral Med Oral Pathol Oral Radiol Endodod. 2008;105:210-5.

  22. Philipsen HP, Reichart PA. Adenomatoid odontogenic tumour: facts and figures. Oral Oncol. 1999;35:125–31.

  23. Leon JE, Mata GM, Frefnani ER, Carlos-Bregni R, de Almeida OP, Mosqueda-Taylor A, et al. Clinicopathological and immunohistochemical study of 39 cases of Adenomatoid Odontogenic Tumour: a multicentric study. Oral Oncol. 2005;41:835-42.

  24. Modolo F, Biz MT, Martins MT, Machado de Sousa SO, de Araújo NS. Expression of extracellular matrix proteins in adenomatoid odontogenic tumor. J Oral Pathol Med. 201;39(3):230-5.

  25. Ide F, Mishima K, Saito I, Kusama K. Diagnostically challenging epithelial odontogenic tumors: a selective review of 7 jawbone lesions. Head Neck Pathol. 2009;3(1):18-26.

  26. Dare A, Yamaguchi A, Yoshiki S, Okano T. Limitation of panoramic radiography in diagnosing adenomatoid odontogenic tumors. Oral Surg Oral Med Oral Pathol. 1994;77:662-8.

  27. Asaumi J, Yanagi Y, Konouchi H, Hisatomi M, Matsuzaki H, Shigehara H, Kishi K. Assessment of MRI and dynamic contrast-enhanced MRI in the differential diagnosis of adenomatoid odontogenic tumor. Eur J Radiol. 2004;51:252–6.

  28. Vasconcelos BC, Frota R, Cardoso AB, Porto GG, Carneiro SC. Adenomatoid odontogenic tumor. Braz J Otorhinolaryngol. 2008;74(2):315.

  29. Swasdison S, Dhanuthai K, Jainkittivong A, Philipsen HP. Adenomatoid odontogenic tumors: an analysis of 67 cases in a Thai population. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;105(2):210-5.

  30. Zhou Chuan-Xiang, Gao Yan. Adenomatoid odontogenic tumor: a report of a rare case with recurrence. J Oral Pathol Med. 2007;36:440-3.

  31. Shetty K, Vastardis S, Giannini P. Management of an unusually large adenomatoid odontogenic tumor. Oral Oncol EXTRA. 2005;41:316-8.

  32. Li BB, Xie XY, Jia SN. Adenomatoid odontogenic tumor with fibro-osseous reaction in the surrounding tissue. J Craniofac Surg. 2013;24(1):e100-101.




2020     |     www.medigraphic.com