2011, Number 3
<< Back Next >>
Rev Mex Angiol 2011; 39 (3)
Tromboembolismo pulmonar asintomático en pacientes con trombosis venosa profunda
Olarte-Casas MÁ, Rojas-Reyna GA, García-Ortiz JR, Schalch PJM, Ríos NMÁ
Language: Spanish
References: 27
Page: 100-106
PDF size: 35.64 Kb.
ABSTRACT
Background: A high frequency of asymptomatic pulmonary embolism (PE) has been reported in patients with deep venous thrombosis (DVT).
Objectives: To estimate the incidence of asymptomatic PE using ventilation/perfusion lung scan in patients with DVT and describe their risk factors.
Material and methods: Ventilation/perfusion lung scans were evaluated in patients without symptoms of PE and proven DVT (assessed by Doppler ultrasonography), from January 2009 through March 2010 in the Nuclear Medicine Service, at the ABC Medical Center, campus Observatorio.
Results: 48% of patients with DVT (70% proximal and 30% distal) had gammagraphic evidence of asymptomatic PE. Smoking, estrogenic hormonal therapy and cancer were factors with relative risk (RR › 1.0) but only the last two were statistically significant (p ‹ 0.05).
Conclusions: The high incidence of asymptomatic PE in patients with DVT, suggests the importance to perform a baseline ventilation/perfusion lung scan, in view that is sensitive and noninvasive.
REFERENCES
Folch-Pi W. Venous thrombosis: an account of the first documented case. JAMA 1974; 228: 195-6.
Wood KE. A history of pulmonary embolism and deep venous thrombosis. Crit Care Clin 2009; 25: 115-31.
Dalen JE. Pulmonary embolism: what have we learned since Virchow? Natural history, pathophysiology, and diagnosis. Chest 2002; 122: 1440-56.
Cervantes J, Rojas G. Virchow’s legacy: deep vein thrombosis and pulmonary embolism. World J Surg 2005; 29: s30-s34.
Picot J. Lecons de clinique medicale. Paris: Masson; 1884.
Alpert JS, Smith R, Carlson J, et al. Mortality in patients treated for pulmonary embolism. JAMA 1976; 236: 1477-80.
Rubinstein I, Murray D, Hoffstein V. Fatal pulmonary emboli in hospitalized patients: an autopsy study. Arch Intern Med 1988; 148: 1425-6.
Roy PM, Colombert I, Durieux P, et al: Systemic review and meta-analysis of strategies for the diagnosis of suspected pulmonary embolism. Br Med J 2005; 331: 259.
White RH. The epidemiology of venous thromboembolism. Circulation 2003; 107 (23, Suppl. 1): 14-8.
Silverstein MD, Heit JA, Mohr DN, et al. Trends in the incidence of deep vein thrombosis and pulmonary embolism: a 25-year population-based study. Arch Intern Med 1998; 158: 585–93.
Sandler DA, Martin JF. Autopsy proven pulmonary embolism in hospital patients: are we detecting enough deep vein thrombosis? J R Soc Med 1989; 82: 203-5.
Heit JA, Cohen AT, Anderson FA. VTE Impact Assessment Group. Estimated annual number of incident and recurrent, non-fatal and fatal venous thromboembolism (VTE) events in the U. S. Blood 2005; 106: 267a.
Carson JS, Kelley MA, Duff A, Weg JG, Fulkerson WJ, Palevsky HI, et al. The clinical course of pulmonary embolism. N Engl J Med 1992; 326: 1240-5.
Sigler L, Romero T, Meillón LA, Gutiérrez L, Aguirre GJ, Esparza C. Tromboembolia pulmonar en un período de 10 años. Rev Med IMSS 1996; 34: 7-11.
Sandoval ZJ, Martínez GML, Gómez A, Palomar A, Pulido T, Zevallos M. PAC Cardio. 1. Tromboembolia pulmonar aguda. México, DF.: Sociedad Mexicana de Cardiología, Editorial Intersistemas; 1998, p. 7-9.
Meigan M. Systematic lung reveal a high frequency of silent pulmonary embolism in patients with proximal deep venous thrombosis. Arch Intern Med 2000; 160: 159-64.
Moser KM. Frequent asymptomatic pulmonary embolism in patients with deep venous thrombosis. JAMA 1994; 271: 223-5.
Menno V. Unexpected high prevalence of silent pulmonary embolism in patients with deep venous thrombosis. Chest 1989; 95: 498-502.
Elgazzar AH. The pathophysiologic basis of nuclear medicine. 2nd. Ed. Elsevier; 2006, p. 305-27.
Hatabu H, Uematsu H, Nguyen B. CT and MR in pulmonary embolism: a changing role for nuclear medicine in diagnostic strategy. Semin Nucl Med 2002; 32: 183-92.
Winer-Muram HT, Rydberg J, Johnson MS, et al. Suspected acute pulmonary embolism: evaluation with multidetector row CT versus digital substraction pulmonary arteriography. Radiology 2004; 233: 806-15.
Stein PD, Fowler SE, Goodman LR, et al. Multidetector computed tomography for acute pulmonary embolism. N Engl J Med 2006; 354: 2317-27.
Huisman MV, Büller HR, Cate JW, Vreeken J. Serial impedance plethysmography for suspected deep venous thrombosis in out patients: the Amsterdam general practitioner study. N Engl J Med 1986; 314: 823-8.
McRae S, Tran H, Schulman S, et al. Effect of patient’s sex on risk of recurrent venous thromboembolism: a meta-analysis. Lancet 2006; 368: 371.
Hoibraaten E, Qvigstad E, Amesen H, et al. Increased risk of recurrent venous thromboembolism during hormone replacement therapy: results of the randomized, double-blind, placebo-controlled estrogen in venous thromboembolism trial (EVTET). Thromb Haemost 2000; 84: 961.
Ochoa Carrillo FJ, Carrillo Esper R, Escudero de los Ríos PM, Meillon García Il, Martínez Zubieta R, Rojas G. Parámetros de práctica clínica basados en evidencia en tromboprofilaxis: diagnóstico y tratamiento de la enfermedad tromboembólica en el paciente con cáncer. GAMO 2009; 8(Supl. 4): 7-27.
Stein PD, Beemath A, Matta F, et al. Clinical characteristics of patients with acute pulmonary embolism: data from PIOPED II. Am J Med 2007; 120: 871-9.