medigraphic.com

2012, Number 4

<< Back

Vet Mex 2012; 43 (4)

Xanthinuria: a rare cause of urolithiasis in the cat

Del-Ángel-Caraza J, Pérez-García CC, Quijano-Hernández IA, Mendoza-López CI, Diez-Prieto I, Martínez-Castañeda JS

Language: English/Spanish
References: 24
Page: 317-325
PDF size: 673.75 Kb.


ABSTRACT

Xanthinuria is a very rare disease in cats. Its etiology may have a genetic origin or may be due to an iatrogenic xanthine- dehydrogenase inhibition that finally results in urolithiasis. The present work reports two cases of xanthine urolithiasis in European Shorthair unrelated male and female cats. Both uroliths were analyzed by stereoscopic microscopy, infrared spectroscopy and scanning electron microscopy. Besides the report of these two clinical cases, a detailed pathophysiologic review and some updated recommendations for diagnosis and treatment for this condition were done.


REFERENCES

  1. LEKCHAROENSUK C, OSBORNE CA, LULICH JP. Epidemiologic study of risk factors for lower urinary tract diseases in cats. J Am Vet Med Assoc 2001; 218:1429-1435.

  2. KRUGER JM, OSBORNE CA, GOYAL SM, WICKSTROM SL, JOHNSTON GR, FLETCHER TF et al. Clinical evaluation of cats with lower urinary tract disease. J Am Vet Med Assoc 1991; 199:211-216.

  3. BUFFINGTON CA, CHEW DJ, KENDALL MS, SCRIVANI PV, THOMPSON SB, BLAISDELL JL et al. Clinical evaluation of cats with nonobstructive urinary tract diseases. J Am Vet Med Assoc 1997; 210:46-50.

  4. RECHE A, HAGIWARA MK, MAMIZUKA E. Estudo clínico da doença do trato urinário inferior em gatos domésticos de São Paulo. Braz. J Vet Res Anim Sci São Paulo 1998; 35:69-74.

  5. GERBER B, BORETTI FS, KLEY S, LALUHA P, MÜLLER C, SIEBER N et al. Evaluation of clinical signs and causes of lower urinary tract disease in European cats. J Small Anim Prac 2005;46:571-577.

  6. SAEVIC BK, TRANGERUD C, OTTESEN N, SORUM H, EGGERTSDÓTTIR AV. Causes of lower urinary tract disease in Norwegian cats. J Fel Med Surg 2011; 13:410-417.

  7. CANNON AB, WESTROPP JL, RUBY AL, KASS PH. Evaluation of trends in urolith composition in cats: 5,230 cases (1985-2004). J Am Vet Med Assoc 2007; 231:570-576.

  8. HOUSTON DM, MOORE AEP. Canine and feline urolithiasis: Examination of over 50000 urolith submissions to the Canadian Veterinary Urolith Centre from 1998 to 2008. Can Vet J 2009; 50:1263-1268.

  9. OSBORNE CA, LULICH JP, KRUGER JM, ULRICH LK, KOEHLER LA. Analysis of 451,891 canine uroliths, feline uroliths, and feline urethral plugs from 1981 to 2007: perspectives from the Minnesota Urolith Center. Vet Clin North Am Small Anim Pract 2009; 39:183-197.

  10. HESSE A, NEIGER R. Urinary stones in cats. In: HESSE A, NEIGER R, editors. A color handbook of urinary stones in small animal medicine. London: Manson- Publishing, 2009:105-131.

  11. OSBORNE CA, LULICH JP, LEKCHAROENSUK C, ALBASAN A, KOEHLER LA, CARPENTER KA et al. Feline xanthine urolithiasis: A newly recognized cause of feline lower urinary tract disease. Proceedings of the American College of Veterinary Internal Medicine Forum; 2003 June 4-7; Charlotte, USA: ACVIM Forum, 2003:781-782.

  12. OSBORNE CA, LULICH JP, POLZIN DJ, SANDERSON SL, KOEHLER LA, ULRICH LK et al. Analysis of 77,000 canine uroliths. Vet Clin North Am Small Anim Pract 1999; 29:17-38.

  13. OSBORNE CA, LULICH JP, SWANSON LL, ALBASAN H. Drug-induced urolithiasis. Vet Clin North Am Small Anim Pract 2009; 39:55-63.

  14. LING GV, RUBY AL, HARROLD DR, JOHNSON DL.Xanthine-containing urinary calculi in dogs given allopurinol. J Am Vet Med Assoc 1991; 198:1935–1940.

  15. KUCERA J, BULKOVA T, RYCHLA R, JAHN P. Bilateral xanthine nephrolithiasis in a dog. J Small Anim Pract 1997; 38:302-305.

  16. FLEGEL T, FREISTADT R, HAIDER W. Xanthine urolithiasis in a Dachshund. Vet Rec 1998; 143:420-423.

  17. VAN ZUILEN CD, NICKEL RF, VAN DIJK TH, REJINGOUD DJ. Xanthinuria in a family of Cavalier King Charles Spaniels. Vet Q 1997; 19:172-174.

  18. WHITE RN, TICK NT, WHITE HL. Naturally occurring xanthine urolithiasis in a domestic shorthair cat. J Small Anim Pract 1997; 38:299-301.

  19. TSUCHIDA S, KAGI A, KOYAMA H, TAGAWA M. Xanthine urolithiasis in a cat: a case report and evalua- tion of candidate gene for xanthine dehydrogenase. J Feline Med Surg 2007; 9:503-508.

  20. SHWEIGHAUSER A, HOWARD J, MALIK Y, FRANCEY T. Xanthinuria in a domestic shorthair cat. Vet Rec 2009; 164,:91-92.

  21. MIRANDA M, RIGUEIRA L, SUAREZ ML, CARBAJALES P, MOURE P, FIDALGO LE et al. Xanthine Nephrolithiasis in a Galician Blond Beef Calf. J Vet Med Science 2010; 72:921-923.

  22. PAIS VM, LOWE G, LALLAAS CD, PREMINGER GM, ASSIMOS DG. Xanthine urolithiasis. Urology 2006; 67(1084.e):9-11.

  23. ARIKYANTS N, SARKISSIAN A, HESSE A, EGGERMANN, LEUMAN E, STEINMANN B. Xanthinuria type 1: a rare cause of urolithiasis. Pediatr Nephrol 2007; 22:310-314.

  24. OSBORNE CA, BARGES JP, LULICH JP, ULRICH L, CARPENTER K, KOHELER L. Feline xanthine urolithiasis: A newly recognized cause of feline lower urinary tract disease. Abstracts of the 10th International Symposium on Urolithiasis; 2004 May 25-28; Hong Kong. Urol Res 2004; 32:171-172.




2020     |     www.medigraphic.com