2013, Number 2
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Otorrinolaringología 2013; 58 (2)
Juvenile nasopharyngeal angiofibroma, Experience in a general hospital
Lamadrid BE, Guerrero ED, González RT, Azuara PE, Hernández OF
Language: Spanish
References: 35
Page: 79-86
PDF size: 410.74 Kb.
ABSTRACT
Background
Juvenile nasopharyngeal angiofibroma is a tumor composed of a
fibrous stroma and irregular blood vessels without middle muscular
layer, which bleed easily. It represents 0.05% of head and neck tumors
and it is more common in young men. The juvenile nasopharyngeal
angiofibroma exhibit slow growth and are clinically manifested by
the invasion of adjacent structures. Surgery remains the first choice
treatment. Recurrence reflects an incomplete initial resection.
Objective
To document the incidence of juvenile nasopharyngeal angiofibroma
at Hospital General de Mexico from 2008 to 2010.
Material and method
A case series, retrospective, cross-sectional, descriptive and observational
study. We conducted a review of medical records and data
collection. The results were reported as descriptive statistics.
Results
Thirty-one cases were diagnosed with juvenile nasopharyngeal angiofibroma.
Patient demographics, symptoms, physical characteristics of
the tumor, the results of imaging studies and angiography, treatment
and surgical approach were reported in each case, as well as type of
anesthesia used in each patient and postoperative bleeding.
Conclusions
Juvenile nasopharyngeal angiofibroma is a high incidence benign
tumor in Mexico, occurring mostly in young male patients. Symptoms
and tumor characteristics are varied. Image studies for staging and
diagnostic-therapeutic arteriography are needed. The treatment of
choice is surgery.
REFERENCES
Chavolla MR, Labra A. Angiofibroma juvenil nasofaríngeo. Meta-análisis de su tratamiento. Rev Med Hosp Gen Mex 2003;66:71-79.
Escajadillo JR. Tumores de nariz y senos paranasales. En: Escajadillo JR, editor. Oídos, nariz, garganta y cirugía de cabeza y cuello. México: El Manual Moderno, 2000;350-351.
Patrick JG, Davidson J. Juvenile angiofibroma: A review of the literature and a case series report. Laryngoscope 1992;102:928-933.
Ungkanont K, Byers RM, Weber RS. Juvenile nasopharyngeal angiofibroma. An update of therapeutic management. Head Neck Surg 1996;18:60-66.
Maharaj D, Fernández C. Surgical experience whith juvenile nasopharyngeal angiofibroma. Ann Otol Rhinol Laryngol 1989;98:269-272.
Rogers DJ, Bevans SE, Harsha WJ. Endoscopic resection of juvenile nasopharyngeal angiofibroma. Adv Otorhinolaryngol 2012;73:132-136.
Pierson B, Powitzky R, Digoy GP. Endoscopic coblation for the treatment of advanced juvenile nasopharyngeal angiofibroma. Ear Nose Throat J 2012;91:432-438.
Kau R, Tanna M, Misra S, Contreras AL. Nasopharyngeal angiofibroma. Ear Nose Throat J 2008;87:256.
Cherekaev VA, Golbin DA, Kapitanov DN, Roginsky VV, et al. Advanced craniofacial juvenile nasopharyngeal angiofibroma. Description of surgical series, case report, and review of literature. Acta Neurochir (Wien) 2011;153:499-508.
Nicolai P, Schreiber A, Bolzoni-Villaret A. Juvenile angiofibroma: evolution of management. Int J Pediatr 2012;2012:412-545.
Tapia R. The nasopharyngeal fibroma and its treatment. Arch Otolaryngol 1956;64:451-455.
Tapia R. Nasopharyngeal fibroma. Acta Otolaryngol (Skotch) 1973;119:26.
Harrison D. The natural history, pathogenesis, and treatment of juvenile angiofibroma. Arch Otolaryngol Head Neck Surg 1987;113:936-942.
Iannetti G, Belli E, de Ponte F, Cicconetti A, Delfini R. The surgical approaches to nasopharyngeal angiofibroma. J Craniomaxillofac Surg 1994;22:311-316.
Lloyd G, Foward D. Juvenile angiofibroma: the lessons of 20 years of modern imaging. J Laryngol Otol 1999;113:127-134.
Blount A, Riley KO, Woodworth BA. Juvenile nasopharyngeal angiofibroma. Otolaryngol Clin North Am 2011;44:989-1004.
Yadav SP, Singh I. Nasopharyngeal angiofibroma. J Otolaryngol 2002;31:346-350.
Pino-Rivero V, Álvarez J. Nasopharyngeal angiofibroma. Our experience (1990-2001). An Otorrinolaringol Ibero AM 2003;30:257-264.
Arroyo M, Martin L. Angiofibroma nasofaríngeo juvenil, experiencia de 10 años: 1979 a 1988. An Soc Mex Otorrinolaringol 1989;XXXIV:302-311.
Lee KJ. Otorrinolaringología y cirugía de cabeza y cuello. 7ª ed. Ciudad de México: McGraw-Hill, 1999;967.
Andrade J, Fajardo J. Nasopharyngeal angiofibroma in the elderly: Report of a case. Laryngoscope 1975;85:1063-1065.
Llorente JL, López F, Suárez V, Costales M, Suárez C. Evolution in the treatment of juvenile nasopharyngeal angiofibroma. Acta Otorrinolaringol Esp 2011;62:279-286.
Mann WJ, Jecker P. Juvenile angiofibromas: Changing surgical concept over the last 20 years. Laryngoscope 2004;11:291-293.
Ogawa AI, Fornazieri MA, da Silva LV, Pinna FR, et al. Juvenile angiofibroma: major and minor complications of preoperative embolization. Rhinology 2012;50:199-202.
Pastor-Quirante FA. Angiofibroma nasal: A propósito de un caso de presentación en la edad adulta. Anales ORL Iber Amer 1993;XXI:479-486.
Kamel R. Transnasal endoscopic surgery in juvenile nasopharyngeal angiofibroma. J Laryngol Otol 1996;110:962-968.
Fyrmpas G, Konstantinidis I, Constantinidis J. Endoscopic treatment of juvenile nasopharyngeal angiofibromas: our experience and review of the literature. Eur Arch Otorhinolaryngol 2012;269:523-529.
Arrieta J, Bross D. Cirugía endoscópica en angiofibroma juvenil. Experiencia en nueve pacientes. An Orl Mex 1997;42:78-83.
Economou TS, Abemayor E. Juvenile nasopharyngeal angiofibroma: an update of the UCLA experience. Laryngoscope 1988;98:170-175.
Radkowski D, Mcgill T. Angiofibroma. Changes in staging and treatment. Arch Otolaryngol Head Neck Surg 1996;122:122-129.
Neel HB, Fee WE. Beningn and malignant tumors of the nasopharynx. Chapter 79. In: Cummings C, editor. Otolaryngology Head & Neck Surgery. 3rd ed. St. Louis, Missouri: Mosby, 1998;1512-1526.
Schiff M, González AM. Juvenile nasopharyngeal contain an aniogenic grow factor: basic FGF. Laryngoscope 1992;102:940-945.
Liang J, Lianq P. The nature of juvenile nasopharyngeal angiofibroma. Otolaryngol Head Neck Surg 2000;123:475-481.
Coutinho CM, Bassini AS. Genetic alterations in Ki-ras and Ha-ras genes in juvenile nasopharyngeal angiofibromas and head and neck cancer. Sao Paulo Med J 1999;117:113-120.
Brieger J, Wierbicka M. Vessel density, proliferation, and immunolocalization of vascular endothelial growth factor in juvenile nasopharyngeal angiofibromas. Arch Otolaryngol Head Neck Surg 2004;130:727-731.