Rodríguez MA, Valencia RHS, Altamirano JT

Language: Spanish
References: 27
Page: 257-263
PDF size: 215.10 Kb.

ABSTRACT

Introduction. The cirrhosis is a frequent suffering, with a high mortality in our country. The etiology is changed, being the first reasons: abuse of alcohol, virus of the hepatitis C and autoimmune hepatopathy. The complications are the most frequent reason of internment in the diverse services of gastroenterology. Objective. To investigate the reasons and the most frequent complications of the cirrhosis in the Hospital Juarez of Mexico. Material and methods. There was realized a retrospective, longitudinal and descriptive study, for which 236 processes of the year 2004 to 2006 were checked. Results. The average of age was 55.7 years with predominance of the masculine genre, especially in the cirrhosis caused by alcohol. The most frequent reasons were alcohol (57.4%), virus of the hepatitis C (26.7%) and autoimmune hepatopathy (15.6%). The complications that prevailed were: dropsy, encephalopathy, digestive hemorrhage, spontaneous peritonitis and hepatorrenal syndrome, in this order. The reasons of mortality were: digestive hemorrhage (54%), hepatic encephalopathy (29%), spontaneous peritonitis (10%) and hepatorrenal syndrome (7.0%). The whole of deaths was 109 cases: 62.4% of the masculine sex and 37.6% of the feminine sex. Commentary. There is needed a major number of epidemiological studies to be able to determine with major precision the prevalence of the etiology and the complications of the cirrhosis that prevails in our way. Nevertheless, these results provide an idea of the existing panorama in our country. It is necessary take more radical and effective measurements that allow the early detection and the prevention of the excessive consumption of alcohol and of the infections for virus of the hepatitis C.

REFERENCES

1. Vesalius A. De humani corporis fabrica libri septem. Basel; 1543, libri V, cap 8, 624.

2. Carswel R. Pathological anatomy Illustrations of the elementary forms of disease. London: Longman; 1838.

3. Von Rokistanski C. Handbuch der pathology anatomie. Wein Braummuler, Seidel; 1849.

4. Anthony PP, Ishak KG, Nayak NC, et al. The morphology of cirrhosis: definition, nomenclature, and classification. Bull World Health Organ 1977; 55: 521-40.

5. Friedman SL. Liver fibrosis-from bench to bedside. J Hepatol 2003; 38: S38-S53.

6. Browning JD, Kumar KS, Saboorian MH, et al. Ethnic differences in the prevalence of cryptogenic cirrhosis. Am J Gastroenterol 2004; 99: 292-8.

7. Sánchez FA, Burguera CM. Hepatitis autoinmune: Concepto, clasificación, criterios diagnósticos, tratamiento. Medicine 1996; 7(9): 374-78.

8. Rodriguez HJ, Bass NM. Primary sclerosing colangitis. Semin Gastrointest Dis 2003; 14: 189-98.

9. Davenport M, Hadzic N. Prenatal diagnosis of liver and biliary trac disease. Semin Neonatal 2003; 8: 347-55.

10. Monterrubio D, Marin E, Larrauri J, et al. Epidemiología de la cirrosis hepática en la ciudad de Puebla. Rev Gastroenterol Mex 1987; 52: 175-8.

11. Reyes B, Márquez C. Correlación entre cirrosis hepática y desnutrición. Rev Gastroenterol Mex 1996; 61: S89.

12. Rodríguez-Hernández H, Guerrero JF, Jacobo JS, et al. Análisis de supervivencia en pacientes cirróticos. Rev Gastroenterol Mex 1996; 61: 226-32.

13. Martínez de los Santos G, Rodríguez AM. Epidemiología de la cirrosis por alcohol en el Hospital Juárez de México. Rev Hosp Jua Mex 1994; 61: 226-32.

14. Boyer TD. Portal hypertensive hemorrhage: pathogenesis and risk factors. Semin Gastrointest Dis 1995; 6: 125.

15. Comar KM, Sanyal AJ. Portal hypertensive bleeding. Gastroenterol Clin North Am 2003; 32: 1079-105.

16. Arroyo V. Pathophysiology, diagnosis and treatment of ascites in cirrhosis. Ann Hepatol 2002; 1: 72-9.

17. Bosh J, Arroyo V, Betriu A, et al. Hepatic hemodynamic and the rennin-angiotensin-aldosterone system in cirrhosis. Gastroenterology 1980; 78: 92-9.

18. Mowat C, Stanley AJ. Review article: Spontaneous bacterial peritonitis-diagnosis, treatment and prevention. Aliment Pharmacol Ther 2001; 15: 1851-9.

19. Lenz K, Kapral C, Gegenhuber A, et al. Systemic, renal, and hepatic hemodynamic derangement in cirrhotic patients with spontaneous bacterial peritonitis. Hepathology 2004; 39: 865-6.

20. Moreau R. The growing evidence that renal function should be improved in patients with cirrhosis and hepatorrenal syndrome before liver transplantation. J Hepatol 2004; 40: 159-61.

21. Gines P, Guevara M, Arroyo V, et al. Hepatorrenal syndrome. Lancet 2003; 362: 1819-27.

22. Vaquero J, Chung C, Blei AT. Brain edema in acute liver failure. A window to the pathogenesis of hepatic encephalopathy. Ann Hepatol 2002; 2: 12-22.

23. Lizardi-Cervera J, Almeda P, Guevara L, et al. Hepatic encephalopathy: a review. Ann Hepatol 2003; 2: 122-30.

24. Mendez-Sanchez N, et al. Etiology of Liver Cirrhosis in Mexico. Annals of Hepathology 2004; 3(1): 30-3.

25. Campollo O, Valencia-Salinas, et al. Epidemiological characteristics of liver cirrhosis at the Hospital Civil of Guadalajara. Salud Pública Mex 1997; 39: 195-200.

26. Hepatitis C –Global prevalence (update). Wkly Epidemiol Rec 1999; 74: 425-7.

27. Frenk J, Lozano R, González M. Economía y salud: propuesta para el avance de salud en México. Informe final. México: Fundación Mexicana para la Salud; 1994.