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2008, Number 3

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Rev Hosp Jua Mex 2008; 75 (3)

Phase two on-transient VO2 kinetics is slow age-related during submaximal exercise in adult men

Padilla J, Kowalchuk JM, Taylor AW, Paterson DH

Language: English
References: 64
Page: 166-182
PDF size: 602.55 Kb.


ABSTRACT

Introduction. The magnitude and time course of muscle oxygen (VO2) consumption (VO2M) is reflected in that of pulmonary VO2 uptake (VO2, mL•min-1) in terms of three on transient phases of response; the cardio dynamic one (Φ1 VO2), the exercise steady state or slow component (Φ3 VO2) and that one (Φ2 VO2) reflecting the VO2M. The Φ2 VO2 on transient response kinetics (ԏ, time constant, s) remains important in gaining insights into VO2M and the degree of a living system Φ2 VO2 ԏ entropy (S Φ2 VO2 ԏ , cal•ºC-1•s). Material and methods. Eight young (YG = 25 ± 3 yrs; mean ± sd) and nine (OG = 71 ± 5) male subjects performed a one legs cycling exercise ramp test (YG: 25W•min-1; OG: 15W•min-1). Each subject completed 4 8 repetitions under each of one moderate (absolute: 50W) and two relative to the estimated ventilatory threshold (θL; moderate: 80%θL, heavy: 120%θL) intensity legs cycling exercise (submaximal= moderate + heavy) lasting 6 min. We compared the Φ2 VO2 ԏ of YG and OG, provided by the breath by breath VO2 data modelled by non linear regression with the best physiologically isolated Φ2 VO2 fit (fitting window: from BaseLine_Start to End) previously tested with two and three component exponential model for moderate and heavy, respectivelly. The relative was determined from a ramp test to put at the same energy exercise level our subjects. Results. We observed the slow Φ2 VO2 kinetics characteristic of the exercise response of old men compared young men (ԏ2: OG › YG), not only for relative (moderate: 62 ± 16 › 28 ± 10, heavy: 40 ± 7 › 26 ± 10) but also for absolute (52 ± 13 › 23 ± 12) (submaximal: 51.3 ± 15.1 › 25.7 ± 10.3), and for the S Φ2 VO2 ԏ (x10-3) for moderate (Sԏ2absolute: 14 ± 1 › 11 ± 2, Sԏ2relative: 15 ± 1 › 12 ± 1), heavy Sԏ2 (13 ± 1 › 12 ± 2) and submaximal Sԏ2: 14 ± 1 › 12 ± 2 as well. Conclusion. The slow Φ2 VO2 kinetics and its increased entropy were age related for both the same energy exercise level (relative) and absolute work rate constant load exercise tests.


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