2013, Number 2
<< Back Next >>
Rev Med Inst Mex Seguro Soc 2013; 51 (2)
Children hospitalized with influenza A H1N1. The field of private care during the pandemic in Mexico
Iglesias-Leboreiro J, Rendón-Macías ME, Marín-Romero M, Bernárdez-Zapata I, López-Enríquez CC
Language: Spanish
References: 31
Page: 130-135
PDF size: 104.37 Kb.
ABSTRACT
Background: the pandemic influenza A H1N1 generated a lot of concern
about its potential lethality, because the constant death reported by
the media. Our objective was to analyze the clinical characteristics and
evolution of children hospitalized in private hospital.
Methods: we included all patients hospitalized since April 2009 to March
2010 with influenza A H1N1 confi rmed by RT-PCR test. The clinical data,
imaging studies and treatment and outcome (hospital stay, PICU admission,
and deaths) were analyzed.
Results: 50 children were hospitalized 15 less than 3 years old (30 %),
23 from 3 to 5 years (46 %), and 12 older than 5 years (24 %). Any
patient required an intensive pediatric care, and there were not deaths.
86 % were admitted for fever, and 40 % with light or moderate respiratory
distress symptoms. In 20 patients a radiologic evidence of interstitial
infiltration (ten) or pneumonia condensation (four) or airways obstruction
(six) were observed. All received oseltamivir treatment and four antibiotic
therapies. The median of hospital stay was 48 hours (24 to 72 hours). All
were egressed without any complication.
Conclusions: benign evolutions were seeing in the children studied.
REFERENCES
Echavarría-Zuno S, Mejía-Aranguré JM, Mar-Obeso AJ, Grajales-Muñoz C, Robles-Pérez E, González-León M, et al. Infection and death from influenza A H1N1 virus in Mexico: a retrospective analysis. Lancet. 2009;374(9707):2072-9.
Karageorgopoulos DE, Vouloumanou EK, Korbila IP, Kapaskelis A, Falagas ME. Age distribution of cases of 2009 (H1N1) pandemic infl uenza in comparison with seasonal influenza. Plos One. 2011;6(7):e21690. Texto libre en http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128617/
Gastañaduy AS, Bégué RE. Experience with pandemic 2009 H1N1 infl uenza in a large pediatric hospital. South Med J. 2012;105(4):192-8.
Miranda-Choque W, Ramírez C, Candela-Herrera J, Díaz J, Fernández A, Kolevic L, et al. Niños hospitalizados con neumonía por infl uenza AH1N1/2009 pandémico en un hospital de referencia de Perú. Rev Peru Med Exp Salud Publica. 2011;28(4):610-6. Texto libre en http://www.scielo.org.pe/scielo.php?pid=S1726-46342011000400006&script=sci_arttext
Tamma PD, Turnbull AE, Milestone AM, Cosgrove SE, Valsamakis A, Budd A, et al. Clinical outcomes of seasonal infl uenza and pandemic influenza A (H1N1) in pediatric inpatients. BMC Pediatric. 2010;10:72. Texto libre en http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978207/
Kendirli T, Demirkol D, Yildizdas D, Anil AB, Asilioglu N, Karapinar B, et al. Critically ill children with pandemic infl uenza (H1N1) in pediatric intensive care units in Turkey. Pediatr Crit Care Med. 2012;13(1):e11-7.
Kedia S, Stroud B, Parsons J, Schreiner T, Curtis DJ, Bagdure D, et al. Pediatric neurological complications of 2009 pandemic A (H1N1). Arch Neurol. 2011;68(4):455-62.
Sánchez-Huerta G, Matías-Juan N, Domínguez-Basurto M, Pacheco-Ruelas M, Jiménez-Juárez RN. Pediatric hospitalizations for the novel influenza A H1N1/2009. Salud Publica Mex. 2010;52(4):288-9.
Serrano-Sierra A, Pérez-Robles V, Nava-Frías M, Villa-Guillén M. Experiencia en el Hospital Infantil de México Federico Gómez ante la epidemia por el virus FluA/SW H1N1: reporte preliminar. Bol Med Hosp Infant Mex. 2009;66:301-5. Texto libre en http://www.medigraphic.com/pdfs/bmhim/hi-2009/hi094c.pdf
Garrido C, Cano C, Salcedo M, Del Razo R, Alejandre A. Influenza A H1N1 (swine flu) en niños estudiadosen el Instituto Nacional de Enfermedades Respiratorias. Acta Pediatr Mex. 2010;31(4):162-7. Texto libre en http://www.nietoeditores.com.mx/volumen-31-num-4-julio-agosto-2010/2496-influenza-a-h1n1-swine-flu-en-ninos-estudiados-en-el-instituto-nacional-de-enfermedades-respiratorias.html
Pérez-Padilla R, de la Rosa-Zamboni D, Ponce de Leon S, M Hernández, Quiñones-Falconi F, Bautista E, et al. Pneumonia and respiratory failure from Swine-origin Influenza A (H1N1) in Mexico. N Engl J Med. 2009;361(7):680-9.
Engelhard D, Bromberg M, Averbuch D, Tenenbaum A, Goldman D, Kunin M, et al. Increased extent of and risk factors for pandemic (H1N1) 2009 and seasonal influenza among children, Israel. Emerg Infect Dis. 2011;17(9):1740-3. Texto libre en http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322075/
Chiu SS, Chan WH, Wong WH, Chan EL, PeirisJS. Age-mat ched of children hospitalized for 2009 pandemic H1N1 infl uenza with those hospitalized for seasonal H1N1 and H3N2. PloS One. 2011;6(7):e21837. Texto libre en http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140491/
Sasbón JS, Centeno MA, García MD, Boada NB, Lattini BE, Motto EA, et al. Infl uenza A (pH1N1) infection admitted to a pediatric intensive care unit: differences with other respiratory virus. Pediatr Crit Care. 2011;12(3):e136-40. Doi: 10.1097/PCC.0b013e3181e28862.
Lochindarat S, Bunnag T. Clinical presentations of pandemic 2009 infl uenza A (H1N1) virus infection in hospitalized Thai children. J Med Assoc Thai. 2011;94(Suppl 3):S107-12.
Hasegawa M, Okada T, Sakata H, Nakayama E, Fuchigami T, Inamo Y, et al. Pandemic (H1N1) 2009-associated pneumonia in children, Japan. Emer Infec Dis. 2011;17(2):279-82.
Parakh A, Kumar A, Kumar V, Dutta AK, Khare S. Pediatric hospitalizations associated with 2009 pandemic infl uenza A (H1N1): an experience from a tertiary care center in North India. Indian J Pediatr. 2010;77(9):981-5.
Gupta BD, Purohit A. A clinical study of hospitalized H1N1 infected children in Western Rajasthan. J Trop Pediatr. 2011;57(2):87-90.
Libster R, Bugna J, S Coviello, DR Hijano, Dunaiewsky M, Reynoso N, et al. Pediatric hospitalizations associated with 2009 pandemic infl uenza A (H1N1) in Argentina. N Engl J Med. 2010;362(1):45-55.
Glica R, Deceuninck G, De Serres G, Boulianne N, Sauvageau C, Quach C, et al. Effectiveness of pandemic H1N1 vaccine against infl uenza-related hospitalization in children. Pediatrics. 2011;128(5):e1084-91. Texto libre en http://pediatrics.aappublications.org/content/128/5/e1084.long
Dubnov-Raz G, Somech R, Warschawski Y, Eisenberg G, Bujanover Y. Clinical characteristics of children with 2009 pandemic H1N1 infl uenza virus infections. Pediatr Int. 2011;53(4):426-30.
Stein M, Tasher D, Glikman D, Shachor-Meyouhas Y, Barkai G, Yochai AB, et al. Hospitalization of children with infl uenza A (H1N1) virus in Israel during the 2009 outbreak in Israel: a multicenter survey. Arch Pediatr Adolesc Med. 2010;164(11):1015-22.
Ciftci E, Tuygun N, Özdemir H, Tezer H, Sensory G, Devrim I, Dalgic N, Kara A, et al. Clinical and epidemiological features of Turkish children with 2009 pandemic infl uenza A (H1N1) infection: experience for multiple tertiary paediatric centres in Turkey. Scand J Infect Dis. 2011;43(11-12):923-9.
Louie JK, Gavali S, Acosta M, Samiuel MC, Winter K, Jean C, et al. Children hospitalized with 2009 novel influenza A (H1N1) in California. Arch Pediatr Adolesc Med. 2010;164(11):1023-31.
Muhammad-Ismail HI, Tan KK, Leng YL, Pau WS, Razali KA, Mohamaed T, et al. Characteristics of children hospitalized for pandemic (H1N1) 2009, Malaysia. Emerg Infect Dis. 2011;17(4):706-10. Texto libre en http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377409/
del Rosal T, Baquero-Artifao F, Calvo C, Mellado MJ, Moina JC, Santos M, et al. Pandemic H1N1 influenza-associated hospitalizations in children in Madrid, Spain. Infl uenza Other Resp Viruses. 2011;5(6):e544-55.
Lera E, Wörner NT, Sancosmed M, Fàbregas A, Casquero A, Melendo S. Clinical and epidemiological characteristics of patients with influenza A (H1N1) 2009 attended to at the emergency room of a children´s hospital. Eur J Pediatr. 2011; 170(3):371-8.
Da Dalt L, Chillemi CH, Cavicchiolo ME, Bressan S, Calistri A, Palù G, et al. Pandemic infl uenza A (H1N1v) infection in pediatric population: a multicenter study in a North-East area of Italy. Ital J Pediatr. 2011;37:24. Texto libre en http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125342/
Miroballi Y, Baird JS, Zackai S, Cannon JM, Messina M, Rvindranath T, et al. Novel infl uenza A (H1N1) in pediatric care facility in New York City during the first wave of the 2009 pandemic. Arch Pediatr Adolesc Med. 2010;164(1):24-30.
Kumar S, Haven PL, Chusid MJ, Willoughby RE, Simpson P, Henrickson KJ. Clinical and epidemiologic characteristics of children hospitalized with 2009 pandemic H1N1 infl uenza A infection. Pediatr Infect Dis J. 2010;29(7):591-4.
Jouvet P, Hutchison J, Pinto R, Menon K, Rodin R, Choong K, et al. Critical illness in children with influenza A/pH1N1 2009 infection in Canada. Pediatr Crit Care Med. 2010;11(5):603-9.