medigraphic.com
ISSN 0210-5187 (Electronic)

2013, Number 2

<< Back Next >>

Med Cutan Iber Lat Am 2013; 41 (2)

Necrolytic migratory erythema as clue to the diagnosis of glucagonoma syndrome

Ormaechea-Pérez N, Arregui-Murua MA, López-Pestaña A, López-Núñez M, Jaka-Moreno A, Tuneu-Valls A

Language: Spanish
References: 11
Page: 70-73
PDF size: 159.11 Kb.


ABSTRACT

Glucagonoma syndrome is a rare paraneoplasic phenomenon. It is characterized by the existente of necrolytic migratory erythema, diabetes mellitus, weight loss, anemia, stomatitis, diarrhea, neuropsychiatric manifestations and thromboembolic events, associated to an alpha-cell tumor of the pancreas. Early detection provides the cure of the neoplasm by surgical removal. We present a 70-year-old woman with necrolytic migratory erythema as the presenting manifestation of glucagonoma syndrome.


REFERENCES

  1. Echenique Elizondo M, Martínez de Lizarduy I. Glucagonoma and necrolytic migratory erythema. Rev Esp Enferm Dig 2005; 97: 455-7.

  2. Becker SW, Kanh D, Rothman S. Cutaneous manifestations of internal malignant tumors. Arch Dermatol Syphilol 1942; 45: 1069-80.

  3. Remes Troche JM, García de Acevedo B, Zuñiga Varga J, Avila Funes A, Orozco Topeta R. Necrolytic migratoy erythema: a cutaneous clue to glucagonoma syndrome. J Eur Acad Dermatol Venereol 2004; 18: 591- 5.

  4. Gardeazabal J, Eguino P, Díaz JL. Síndrome del glucagonoma. Piel 2001; 16: 278-83.

  5. Mendoza Guil F, Hernández Jurado I, Burkhardt P, Linares J, Naranjo R. Eritema necrolítico migratorio asociado a glucagonoma. Actas Dermosifilogr 2005; 96: 175-8.

  6. Pujol RM, Wang CYE, el-Azhary RA, Su WPD, Gibson LE, Schroeter L. Necrolytic migratory erythema: clinicopathologic study of 13 cases. Int J Dermatology 2004; 43: 12-8.

  7. Hunt SJ, Narus VT, Abell E. Necrolytic migratoy erythema: diskeratotic dermatitis, a clue to early diagnosis. J Am Acad Dermatol 1991; 24: 473-7.

  8. Echenique Elizondo M, Tuneu Valls A, Elorza Orúe J, Martínez de Lizarduy I, Ibánez Aguirre J. Glucagonoma and pseudoglucagonoma syndrome. J Pancreas 2004; 5: 179-85.

  9. Lobo I, Carvalho A, Amaral C, Machado S, Carvalho R. Glucagonoma syndrome and necrolytic migratoy erythema. Int J Dermatology 2010; 49: 24-9.

  10. Kasper CS, Mc Murry K. Necrolytic migratory erythema withour glucagonoma versus canine superficial necrolytic dermatitis: is hepatic impairment a clue to pathogenesis? J Am Acad Dermatol 1991; 25: 534-41.

  11. Teixeira RC, Nico MM, Ghideti AC. Necrolytic migratoy erythema associated with glucagonoma: a report of 2 cases. Clinics 2008; 63: 267-70.




2020     |     www.medigraphic.com