2011, Number 4
Valoración neuropsicológica, afectiva y funcional pre y postquirúrgica de pacientes con enfermedad metastásica en sistema nervioso
Language: Spanish
References: 7
Page: 157-162
PDF size: 390.69 Kb.
ABSTRACT
Objective. Show the neuropsychological findings in patients with NSMD, pre and post neurosurgical treatment at INCan between 2009-2010. Material and methods. In eleven patients with NSMD were practiced neurosurgical metastasectomy. Preoperative and postoperative neuropsychological assessment was performed. Also RTOG prognostic factors, Karnofsky performance status (KPS), anxiety- depression and the Barthel ADL status were evaluated. The variables were: level of consciousness, orientation, attention spam, language, constructional ability, memory, calculation skills, reasoning/ judgment, neurosurgical prognostic factors, anxiety-depression, and activities of daily living autonomy. Results. We find a 1.17 to 12.03 months survival range (average 6.03) with nine alive patients at check day. The cognitive functioning show improvement in the PO, also better KPS’s, improvement in the activities of daily living, and lower anxiety-depression rates. Conclusion. Assessment pre and postoperative times, has become in a valuable tool to base lines establishment in nervous system tumors patients, and it has been demonstrated that the cognitive impairments come from the tumor effect and not from neurosurgical treatment. In regards of that, it’s possible to think and try new surgical approaches.REFERENCES
Shaffrey ME, Mut M, Asher AL, et al. Brain metastases. Curr Probl Surg 2004; 41(8): 665-741; Thomas SS, Dunbar EM. Modern multidisciplinary management of brain metastases. Curr Oncol Rep 2010; 12(1): 34-40. Citados por Kellner CP, D’Ambrosio AL. Surgical Management of Brain Metastases. Neurosurg Clin N Am 2011; 22: 53-9. Doi:10.1016/ j.nec.2010.08.003.
Norden AD, Wen PY, Kesari S. Brain metastases. Curr Opin Neurol 2005; 18(6): 654-61; Gavrilovic IT, Posner JB. Brain metastases: epidemiology and pathophysiology. J Neurooncol 2005; 75(1): 5-14. Citados por Kellner CP, D’Ambrosio AL. Surgical management of brain metastases. Neurosurg Clin N Am 2011; 22: 53-9. Doi:10.1016/ j.nec.2010.08.003.