medigraphic.com
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán

2011, Number 5

<< Back Next >>

Rev Invest Clin 2011; 63 (5)

The importance of habitual vitamin A dietary intake on the serum retinol concentration in the elderly: a population-based study

Carmem-Costa-do-Nascimento C, Cristhine-Pordeus-de-Lima R, Rios-Asciutti LS, Marcos-de-Moraes R, Hermínia-Andrade-e-Silva A, da-Silva-Diniz A, Marinho-Albuquerque T, Rodrigues-Gonçalves MC, Santana-de-Oliveira R, de-Carvalho-Costa MJ

Language: English
References: 54
Page: 450-460
PDF size: 211.97 Kb.


ABSTRACT

Introduction. The aging population is one of the main results of population demographic trends during the twentieth century and will be the hallmark of populations during this century. Objective. To assess the habitual dietary vitamin A intake and serum retinol concentration in the elderly. Material and methods. This is a population-based epidemiological study conducted in João Pessoa, Paraíba, northeastern Brazil, from July 2008 to January 2010, with 212 individuals from 60 to 90 years of age, from both genders. Habitual food intake, retinolemia and C-reactive protein (CRP), as well as socioeconomic and anthropometric data were collected. Results. The median of vitamin A intake was 1643.40 µg EAR/day (p25 = 1112.20-p75 = 2430.80). The average serum retinol concentration was 1.91 ± 0.68 mmol/L. There was no correlation of CRP concentration with serum retinol (r = 0.061/p = 0.424), nor with the habitual dietary retinol intake (r = 0.000/p = 0.932). However, there was a direct relationship between food intake and serum retinol concentration (r = 0.173/p = 0.025). Only 3.98% (IC95% 6.88-1.08) of subjects had inadequate serum retinol concentrations (‹ 1.05 µmol/L), and 12.4% (IC95% 17.36-7.44) had inadequate vitamin A intake (‹ 625 µg for males and ‹ 500 µg for females). Most individuals assessed in this study showed adequate retinolemia state and habitual dietary vitamin A intake, probably protecting them from this specific nutritional vulnerability, and no correlation between CRP concentration and serum and dietary retinol was found, possibly because these individuals had no acute inflammation and absence of chronic decompensated diseases.


REFERENCES

  1. United Nations, Departament of Economic and Social Affairs: population division. World population ageing 2009. New York; 2009, p. 82.

  2. Nascimento AL, Diniz AS, Arruda IKG. Deficiência de vitamina A em idosos do programa de saúde da família de Camaragibe, PE, Brasil. Arch Latinoam Nutr 2007; 57(3): 213-8.

  3. D’Souza AL. Ageing and gut. Postgrad Med J 2007; 83: 44-53.

  4. Campos MTFS, Monteiro JBR, Ornelas APRC. Fatores que afetam o consumo alimentar e a nutrição do idoso. Rev Nutr 2000; 13(3): 157-65.

  5. Timiras PS. Physiological basis of aging and geriatrics. 4th. Ed. VIII. New York: Informa Healthcare; 2007, p. 407.

  6. Oldewage-Theron WH, Samuel FO, Djould RD. Serum concentration and dietary intake of vitamins A and E in low-income South African elderly. Clin Nutr. DOI: 10.1016/ j.clnu.2009.08.001.

  7. Akbaraly TN, Favier A, Berr C. Total plasma carotenoids and mortality in the elderly: results of the epidemiology of vascular ageing (EVA) study. Br J Nutr 2008. DOI: 10.1017/ S0007114508998445. Available from: http://journals.cambridge.org/action/displa Abstract?aid¼1890668 [On line, by Cambridge University 29 May 2008].

  8. Lauretani F, Semba RD, Dayhoff-Brannigan M, Corsi A, Di Iorio A, Buiatti E, et al. Low total plasma carotenoids are independent predictors of mortality among older persons the In-CHIANTI study. Eur J Nutr 2008; 47(6): 335-40.

  9. Thurnham DI, Mccabe GP, Northrop-Clewes CA, Nestel P. Effects of suclinical infarction on plasma retinol concentrations and assessment of prevalence of vitamin A deficiency: metaanalysis. Lancet 2003; 362: 2052-8.

  10. Scheurig AC, Thorand B, Fischer B, Heier M, Koenig W. Association between the intake of vitamins and trace elements from supplements and C-reactive protein: results of the MONICA/KORA Augsburg study. Eur J Clin Nutr 2008; 62: 127-37.

  11. Gey KF, Ducimetière P, Evans A, Amouyel P, Arveiler D, Ferrièresf J, et al. Low plasma retinol predicts coronary events in healthy middle-aged men: The PRIME Study. Atherosclerosis 2010; 208: 270-4.

  12. Kac G, Sichieri R, Gigante DP. Epidemiologia nutricional. Rio de Janeiro: Fiocruz-Atheneu; 2007, p. 580.

  13. WHO. Obesity: preventing and managing the global epidemic. Report of a WHO Consulation Group on Obesity. Geneva: 1998.

  14. Lipschitz DA. Screening for nutritional status in the elderly. Prim Care 1994; 21(1): 55-67.

  15. Lima FELL, Slater B, Latorre MRDO, Fisberg RM. Validade de um questionário quantitativo de frequência alimentar desenvolvido para população feminina no nordeste do Brasil. Rev Bras Epidemiol 2007; 10: 483-90.

  16. Lima FEL, Latorres MRDO, Costa MJC, Fisberg RM. Diet and cancer in northeastern Brazil: evaluation of food and food group consumption in relation to breast cancer. Cad Saude Publica (FIOCRUZ). 2008; 24: 820-8.

  17. Otten JJ, Hellwig JP, Meyers LD. Dietary Reference Intake: the essencial guide to nutrient requirements. Washington: The National Academies Press; 2006, p. 543.

  18. Asciutti LSR, Rivera MAA, Costa MJC, Imperiano E, Arruda MS, Bandeira MG, Arruda NS. Manual de porções média em tamanho real: baseado no programa Dietsys. UFPB 2005.

  19. Furr HC, Tanumihardj O, Olson JA. Training manual for assessing vitamin A status by use of the modified relative dose response and the relative dose response assays Sponsede by the USAID vitamin A. Washington: Field Support Project-Vital; 1992, p. 70.

  20. WHO. Indicators for assessing vitamin A deficiency and their application in monitoring and evaluating intervention programs: Micronutrients series. Geneva: WHO/UNICEF; 1996.

  21. Herbeth B, Siest G, Henny J. Hight-sensivity C-reactive protein (CRP) reference intervals in the elderly. Clin Chem Lab Med 2001; 39: 1169-70.

  22. Development Core R Team: A language and environment for statistical computing. R Foundation for Statistical Computing, Available from: http://www.R-project.org/ Acesso em: 16 de fevereiro de 2010.

  23. Cortês Neri M (coord.). Consumidores produtores e a nova classe média: miséria, desigualdade e determinantes das classes. Rio de Janeiro: FGV/IBRE, CPS; 2009, p. 130.

  24. Oldewage-Theron WH, Kruger R. Food variety and dietary diversity as indicators of the dietary adequacy and health status of an elderly population in Sharpeville, South Africa. J Nutr Elder 2008; 27(1-2): 101-33.

  25. Houston DK, Ding J, Nicklas BJ, Harris TB, Lee JS, Nevitt MC, et al. Overweight and obesity over the adult life course and incident mobility limitation in older adults. Am J Epidemiol 2009; 169(8): 927-36.

  26. Lima ALL, Silva ACF, Konno SC, Conde WL, Benicio MHD, Monteiro CA. Causes of the accelerated decline in child undernutrition in Northeastern Brazil (1986-1996-2006). Rev Saude Pública 2010; 44(1): 17-27.

  27. Neri MC (coord.). Miséria, desigualdade e políticas de renda: o Real do Lula. Rio de Janeiro: Centro de Políticas Sociais e Instituto Brasileiro de Economia da Fundação Getulio Vargas; 2007.

  28. Neutzling MB, Rombaldi AJ, Azevedo MR, Hallal PC. Factors associates with fruit and vegetable intake among adults in a southern Brazilian city. Cad Saude Publica 2009; 25(11): 2365-74.

  29. Ministério da Saúde. Guia Alimentar para a população brasileira: promovendo a alimentação saudável. Secretaria de atenção à saúde: Brasília; 2006.

  30. Philippi ST, Latterza AR, Cruz ATR, Ribeiro LC. Adapted food pyramid: a guide for a right food choice. Rev Nutr Campinas 1999; 12(1): 65-80.

  31. USDA. U.S. Department of Agriculture: U.S. Department of health and human service. Dietary Guidelines for Americans, 2005. Available from: www.healthierus.gov/dietaryguidelines

  32. Sommer A. Vitamin A deficiency and clinical disease: an historical overview. J Nutr 2008; 138: 1835-9.

  33. Goldbohm RA, Brants HAM, Hulshof KFAM, Van Den Brandt PA. The contribution of various foods to intake of vitamin a and carotenoids in the netherlands. Int J Vitam Nutr Res1998; 68: 378-83.

  34. Lucarini M, Lanzi S, D’evoli L, Aguzzi A, Lombardi-Boccia G. Intake of vitamin a and carotenoids from the Italian population- Results of an Italian Total Diet Study. Int J Vitam Nutr Res. Seite 103-109, Band 76, 2006. Doi:10.1024/0300- 9831.76.3.10.

  35. Lauretani F, Semba RD, Dayhoff-Brannigan M, Corsi A, Di Iorio A, Buiatti E, et al. Low total plasma carotenoids are independent predictors of mortality among older persons the In- CHIANTI study. Eur J Nutr 2008; 47(6): 335-40.

  36. Humphreys V, Martin RM, Ratcliffe B, Duthie S, Wood S, Gunnell D, Collins AR. Age-related increases in DNA repair and antioxidant protection: A comparison of the Boyd Orr Cohort of elderly subjects with a younger population sample. Age Ageing.2007; 36: 521-6.

  37. Mecocci P, Polidori MC, Troiano L, Cherubini A, Cecchetti R, Pini G. Plasma antioxidants and longevity: a study on healthy centenarians. Free Radic Biol Med 2000; 28(8): 1243-8.

  38. Stephensen CB, Gildengorin G. Serum retinol, the acute phase response, and the apparent misclassification of vitamin A status in the Third National Health and Nutrition Examination Survey. Am J Clin Nutr 2000; 72: 1170-8.

  39. Cheng WY, Fu ML, Wen LJ, Chen C, Pan WH, Huang CJ. Plasma retinol and α-tocopherol status of the Taiwanese elderly population. Asia Pac J Clin Nutr 2005; 14(3): 256-62.

  40. Polito A, Intorre F, Andriollo-Sanchez M, Azzini E, Raguzzini A, Meunier N, et al. Estimation of intake and status of vitamin A, vitamin E and folate in older European adults: the ZENITH. Eur J Clin Nutr 2005; 59 (Suppl. 2): S42-S47.

  41. Tomita LY, Almeida LC, Roteli-Martins C, D’Almeida V, Cardoso MA. Dietary predictors of serum total carotene in low-income women living in São Paulo, South-east Brazil. Public Health Nutr 2009; 12(11): 2133-42.

  42. Russel RM. The aging process as a modifier of metabolism. Am J Clin Nutr 2000; 72 (Suppl.): S529-S532.

  43. Hankinson SE, Stampfer MJ, Seddon JM, Colditz GA, Rosner B, Speizer FE. Nutrient intake and cataract extraction in women: a prospective study. BMJ 1992; 305(6849): 335-9.

  44. Stahl W, Sie H. Bioactivity and protective effects of natural carotenoids. Biochimica et Biophysica Act 2005; 1740: 101-07.

  45. Mora JR, Iwata M, Andrian UH. Vitamin effects on the immune system: vitamins A and D take centre stage. Nat Rev Immunol 2008; 8(9): 685-98.

  46. Sommer A. Vitamin A deficiency and clinical disease: An historical overview. J Nutr 2008; 138: 1835-9.

  47. Vannucchi H, Cunha DF, Bernades MM, Unamuno MRL. Avaliação dos níveis séricos das vitaminas A, E, C e B2, de carotenóides e zinco, em idosos hospitalizados. Rev Saude Pública1994; 28(2): 121-6.

  48. Bulux J. Studies on the application of the relative-dose-response test for assessing vitamin A status in older adults. Am J Clin Nutr 1992; 56: 543-7.

  49. Costa MJC, Guilland JC, Moreau D, Boggio V. Vitamin status of health subjects in Burgundy (France). Ann Nutr Metab1996; 40: 24-51.

  50. Hallfrisch J, Müller DC, Singh VN. Vitamin A and E intakes and plasma concentrations of retinol, β-carotene, and α-tocopherol in men and women of the Baltimore Longitudinal Study of Aging. Am J Clin Nutr 1994; 60: 176-82.

  51. Ambrósio CLB, Campos CFA, Faro ZP. Carotenoids as an alternative against hypovitaminosis. A Rev Nutr Campinas 2006; 19(2): 233-43.

  52. Albuquerque MN, Diniz AS, Arruda IKG. Retinolemia, consumo de vitamina A e pressão arterial em idosos. Arch Latinoam Nutr 2009; 59(4): 396-401.

  53. National Academy of Sciences. Recommended dietary allowances. 8th. Ed. Washington (DC); 1974.

  54. Ribaya-Mercado JD, Solon FS, Solon MA, Cabal-Barza MA, Perfecto CS, Tang G, et al. Bioconversion of plant carotenoids to vitamin A in Filipino school-aged children varies inversely with vitamin A status. Am J Clin Nutr 2000; 72(2): 455-65.




2020     |     www.medigraphic.com