Leyva GG

Language: Spanish
References: 12
Page: 18-22
PDF size: 95.32 Kb.

ABSTRACT

Nanotechnology has changed the functional perspective of the materials used in medicine, providing a better functionality mainly due to its nanometric size. An example are silver nanoparticles that exhibit different properties once they are applied to biological systems compared with traditional systems of treatment. The nanoscale gives them the ability to penetrate different biological membranes, such as bacterial cell wall thereby increasing their bactericidal effect. The purpose of this review is to address the processes used for obtaining silver nanoparticles, as an example of the technology used in the design of these vehicles, the quality parameters applied to protect its functionality and an explanation of its mechanism of antibacterial action for an effective therapeutic evaluation and as a reference point of impact of the development of materials through nanotechnology.

REFERENCES

1. Appelgren P, Björnhagen V, Bragderyd K, Jonsson CE, Ransjö U. A prospective study of infections in burn patients. Burns 2002; 28: 39-46.

2. Wei D, Sun W, Qian W, Ye Y, Ma X. The synthesis of chitosan-based nanoparticles and their antibacterial activity. Carb Res 2009; 344: 2375-2382.

3. Spadaro D, Barletta E, Barreca F, Currò G, Neri F. Synthesis of PMA stabilized silver nanoparticles by chemical reduction process under a two-step UV irradiation. Appl Surf Sci 2010; 256: 3812-3816.

4. Sahoo SK, Parveen S, Panda JJ. The presence and future of nanotechnology in human health care. Nanomedicine 2007; 3: 20-31.

5. Kreuter J. Nanoparticles– a historical perspective. Int J Pharm 2007; 331: 1-10.

6. Le AT, Tam LT, Tam PD, Huy PT, Huy TQ, Hieu NV et al. Synthesis of oleic acid-stabilized silver nanoparticles and analysis of their antibacterial activity. Mat Sci Eng C 2010; 30: 910-916.

7. Sheikh N, Akhavan A, Kassaee MZ. Synthesis of antibacterial silver nanoparticles by gamma irradiation. Physica E 2009; 42: 132-135.

8. Guzman M, Dille J, Godet S. Synthesis and antibacterial activity of silver nanoparticles against Gram positive and Gram negative bacteria. Nanomed Nanotech Biol Med 2011; 8: 37-45.

9. Sharma VK, Yngard RA, Lin Y. Silver nanoparticles: Green synthesis and their antimicrobial activities. Adv Colloid Interface Sci 2009; 145: 83-96.

10. Le AT, Tam LT, Tam PD, Huy PT, Huy TQ, Hieu NV et al. Synthesis of oleic acid-stabilized silver nanoparticles and analysis of their antibacterial activity. Mater Sci Eng C 2010; 30: 910-916.

11. Breunig M, Bauer S, Goepferich A. Polymers and nanoparticles: Intelligent tools for intracellular targeting? Eur J Pharm Biopharm 2008; 68: 112-128.

12. Zetasizer Nano Series User Manual. Malvern instruments. Worcestershire, UK; 2004.