1999, Number 2
<< Back Next >>
Rev Med Hosp Gen Mex 1999; 62 (2)
Autoimmune polyglandular syndrome type II (Schmidt’s Syndrome). Report of the first case diagnosed in 29,568 autopsies performed in the Hospital General de México
Soriano RJ, Carrera GE, Sánchez PV, Rubio SY, Guevara LB
Language: Spanish
References: 26
Page: 128-131
PDF size: 218.40 Kb.
ABSTRACT
The first case of Autoimmune Polyglandular Syndrome Type II (Schmidt Syndrome) diagnosed among 29,568 autopsies at the pathology unit of Hospital General de Mexico, in Mexico City is reported. A 18 years old woman with type I insulin dependent Diabetes Mellitus was admitted with hydroelectrolitic disorders and right basal pneumonia, she developed respiratory failure and died. The autopsy findings were grade II malnutrition, Hashimoto thyroiditis, lymphoid adrenalitis, ovarian atrophy and right pneumonia. Other endocrine glands were not affected.
REFERENCES
Schmidt MB. Eline biglandulare Erkrankung (Nebennieren und Schilddruse bei Morbus Addisonni). Dutch Pathol Ges 1926; 21: 212-221.
Machlaren NK, Riley WJ. Inherited susceptibility to autoimmune Addison’s disease is linked to human leukocyte antigen-DR3 and/or DR4 except when associated with type I autoimmune polyglandular syndrome. J Clin Endocrinol Metab 1986; 62: 455-459.
Neufeld M, Maclaren NK, Blizzard RM. Two type of autoimmune Addison’s disease in HLA. In: Farid Ned. Endocrine and metabolic disorders. New York: Academic Press 1981; 235-362.
Einsenbarth GS, Wilson P, Ward F et al. HLA type and occurrence of disease in familial polyglandular failure. N Engl J Med 1978; 298: 92-94.
Valenta LG, Bull RW, Mackel E et al. Correlation of the HLA-A-1, B8 aplotypes with circulating autoantibodies in a family with increased incidence of autoimmune disease. Acta Endocrinol 1982; 100: 143-149.
Irving WJ. Autoimmunity in endocrine disease. Recent Prog Horm Res 1980; 46: 509-556.
Stewart SR, Gershwin ME. The associations and relationships of congenital immune deficiency states and autoimmune phenomenon. Semin Arthritis Rheum 1971; 9: 98-123.
Cacci N, Mak TW. T cell receptors. Am J Med 1988; 85: 9-11.
Stankler L, Bewsher PD. Chronic mucocutaneus candidiasis, endocrine deficiency and alopecia areata. Br Dermatol 1972; 86: 238-245.
Brown FM, Freeman R, Tyler HR et al. Polyglandular autoimmune and Parkinson’s disease. Clin Res 1989; 37: 356.
Peserica A. Rigen F, Semmenzoto G et al. Vitiligio and polyglandular disease with autoantibodies to melanin producing cells. Arch Dermatol 1981; 117: 751-752.
Van Thiek DH, Smith WI Jr, Rabin BS et al. A syndrome of immunoglobulin A deficiency, diabetes mellitus, malabsortion, a common HLA aploide type. Immunologic and genetic studies of forty-three family members. Ann Intern Med 1977; 86: 10-19.
Mershon JC, Dietrich JG. Hereditary Addison’s disease and multiple endocrine adenomatosis in a kindred: autoimmune aspect. Ann Inter Med 1966; 65: 252-258.
Bardwitch PA, Avaifler NJ, Gill GN et al. Plasma cell dyscrasia with polineuropathy, organomegaly, endourinopathy, M protein and skin change: The POEMS syndrome. Medicine 1980; 59: 311-322.
Imawari M, Akatsuka N, Ishabashi M et al. Syndrome of plasma cell dyscrasia, polyneuropathy and endocrine disturbances. Ann Inter Med 1974; 81: 490-493.
Iwashita H, Ohnishai A, Asada M et al. Polineuropathy, skin hyperpigmentation edema and hypertrichosis in localized osteosclerotic myeloma. Neurology 1977; 27: 675-681.
Combs RM. Malignant thymoma, hyperthyroidism and immune disorder. South Med J 1968; 81: 337-341.
Le Golvan DP, Abell MR. Thymomas. Cancer 1977; 29: 2142-2157.
Eisenbarth GS, Verge CH. The immunoendocrinopathy syndrome. In: Endocrinology Williams textbook. 9th ed. Philadelphia: WB Saunders, 1998: 1651-1662.
Eisenbart GS. Multihormonal systems and disorders. In: Leslie J, De Groot (eds). Endocrinology. 2nd ed. Philadelphia: WB Saunders, 1998: 2632-2638.
Fertos LJ, Bayard C. Syndrome polyglandular autoinmune. Endocrinología básica y clínica. 4a ed. México: Manual Moderno, 1994: 838-849.
Lack EF. Lymphoid “hypophysitis” with end organ insufficiency. Arch Pathol 1975; 99: 215-219.
Parker M, Klein I, Fixhman LM et al. Silent thyrotoxic thyroiditis in association with chronic adrenocortical insufficiency. Arch Inter Med 1981; 140: 1108-1109.
Irivrn WJ, Scarth L, Clarke EF et al. Thyroid and gastric autoimmunity in patient with diabetes mellitus. Lancet 1970; 2: 163-168.
Ahonen P, Mietinenin A, Pehentup A. Adrenal and steroidal cell antibodies in patients with autoimmune polyglandular disease type I and risk of adrenocortical and antiovarian failure. J Clin Endocrinol Metab 1987; 64: 494-500.
De Lellis R. El sistema endocrino. En: Contran K, Robbins SL (eds). Patología estructural y funcional. 4a ed. Madrid: Interamericana, 1990: 1319.