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ISSN 1025-0255 (Electronic)

2012, Number 5

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AMC 2012; 16 (5)

Association between the treatment of periodontitis and severity of rheumatoid arthritis

Echeverri BE, Henríquez LM, Elena PK, Bernardo RA, Martin AC

Language: Spanish
References: 20
Page: 1602-1610
PDF size: 244.12 Kb.


ABSTRACT

Background: periodontitis and rheumatoid arthritis share several features including a persistent immune response in connective and bone tissue. Objective: to establish the association between periodontal therapy and severity of rheumatoid arthritis, considering clinical and laboratory parameters. Methods: a systematic review was performed including randomized clinical trials that studied the association between periodontal therapy and severity of rheumatoid arthritis. The search for information was conducted from January 1990 to December 2010. Databases like MEDLINE, LILACS, EMBASE and Cochrane Library were reviewed. Selection criteria were based on experimental studies which reported treatment of chronic periodontitis in patients with rheumatoid arthritis. In rheumatologic level were considered those articles which their results were based on the erythrocyte sedimentation rate, rheumatoid factor, and DAS 28 and C-reactive protein levels. From the point of view of the results of periodontal treatment articles, were included variables like: bleeding to probing, probing depth and level of clinical insertion depth. Two reviewers assessed the quality of each study using the CONSORT 2010 guideline. Results: after reviewing the abstracts, 10 articles were found that could be reviewed, of which, only four fulfilled the inclusion criteria. Reduction in the severity of rheumatoid arthritis in terms of disease activity (DAS 28) was observed. Conclusion: the therapeutic control of periodontitis may have a beneficial effect on rheumatoid arthritis, reducing to some extent its severity taking into account the parameters of clinical and laboratory measurement.


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