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2005, Number 2

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Rev Endocrinol Nutr 2005; 13 (2)

Anorexigenic peptides and its participation in the food behaviour

Jaimes L, Cabrera-Wrooman A, Vilches A, Guzmán C, Camacho-Arroyo I

Language: Spanish
References: 84
Page: 67-74
PDF size: 138.88 Kb.


ABSTRACT

Food intake and energy expenditure are regulated by a complex neuroendocrine system consisting of central signals, mainly, neuropeptides and peripheral signals such as leptin. Several neuropeptides with anorexigenic (POMC, CART, CRH TRH, a-MSH, GLP-1 and PYY) as well as orexigenic (NPY, AgRP, and MCH) actions are involved in this complex regulating system. Starvation or food restriction lead to changes in the expression of these neuropeptides, which is also regulated by leptin. In this review the role of important anorexigenic neuropeptides on food intake and body weight regulation is summarized.


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