Morales–Ramírez F

Language: Spanish
References: 15
Page: 107-110
PDF size: 483.75 Kb.

ABSTRACT

Clostridium perfringens is part of the normal human intestinal microbiota, however under certain circumstances such as ischemia, neutropenia and thrombocytopenia, it can become a pathogenous bacteria and be held responsible for a variety of disease. It presents many virulency factors, 12 of wich are toxins, an enterotoxin, a hemolysin and a neuromidase wich provide its pathogenic properties. Diagnosis is made by clinical and pathological data, and is confirmed by the actual growth of the microoganism, biochemical analysis and Enzyme-Linked InmunoSorbent Assay (ELISA). Some of the disease caused by this microorganism are gas gangrene, necrotizing gangrene and acute food poisoning. The first one should be treated aggressively by surgical debridement, the second one with antibiotics and surgical resection of necrotic intestine while the last one will resolve itself in 24 to 48 hours and requires no treatment.

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