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Instituto Nacional de Neurología y Neurocirugía

2012, Number 3

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Arch Neurocien 2012; 17 (3)

Qualitative impact of cognitive impairment on daily life activities of patients with recently diagnosed multiple sclerosis

Jiménez-López JL, Kleinert-Altamirano API, Rodríguez- Galindo DM, Molina-Carrión LE

Language: Spanish
References: 31
Page: 165-171
PDF size: 93.65 Kb.


ABSTRACT

Objective: to know the qualitative impact of cognitive impairment on daily life activities of patients with recently diagnosed multiple sclerosis (MS). Material and methods: patients with MS consecutively diagnosed in the previous six months underwent a neuropsychological test (Programa Integrado de Exploración Neuropsicológica - Test Barcelona) to measure their cognitive function. The daily life activities were assessed using the World Health Organization Disability Assessment Schedule II (WHODAS-II). Associations between impaired cognitive function and daily life activities affected were analyzed using the exact Fisher´s test. Statistical significance was defined as p‹ 0.05. Results: 17 patients were enrolled, 10 females and 7 males. 76% were employed. All of them scored cognitive function under normal percentile of the assessed areas with the exception of some corresponding to language. Only some praxis related functions showed association of statistical significance with mild difficult to carry on well the most important tasks in job. Conclusions: all the patients in this sample with recently diagnosed MS showed subtle cognitive impairment that affected mildly their performance in job. The qualitative assessment, instead of quantitative, of cognitive function in early stage o MS may allow to identify target functions to rehabilitate, with the purpose of delay early retirement of job. These preliminary results need to be confirmed with larger samples using control group.


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