2012, Number 4
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Anales de Radiología México 2012; 11 (4)
Prevalence of incidental nodular lesions of the thyroid gland in PET/CT studies in patients at the PET/CT cyclotron unit, UNAM School of Medicine
Bezaury RP, Contreras ZK, Orozco OÓ, García GJJ
Language: Spanish
References: 15
Page: 219-227
PDF size: 423.68 Kb.
ABSTRACT
Thyroid nodules are common, with 4-8% frequency by palpation
in adults; between 30 and 50% are identified by ultrasound
(US). In autopsies, nodules have been found in 50% of personas
without preexisting thyroid disease.
The PET/CT study, which is performed to evaluate other carcinomas,
can identify focal or diffuse uptake in this gland. When
uptake is diffuse, it is usually attributed to thyroiditis. In contrast,
when uptake is focal, it indicates probability of a carcinoma
in between 30 and 50% of cases. “Incidental” findings in
the thyroid gland have a prevalence of 1.2 to 4.3%. 14 to 50%
are associated with risk of malignant thyroidal pathology. The
maximum standardized uptake value (SUV
max) of malignant and
benign lesions is highly variable, making differentiation based
exclusively on that value nearly impossible.
REFERENCES
Kwak Young Jin, Kim Eun-Kyung, and Yun Mijin, et al. Thyroid incidentalomas identified by 18F-FDG PET: Sonographic Correlation.AJR 2008;191:598-603.
Naik KS, Bury RF. Imaging the thyroid. Clinical Radiology 1998;53:630-639.
Thyroid carcinoma. National Comprehensive Cancer Network. www.nccn.org/professionals/physician_gls/PDF/ thyroid.pdf
Kim TY, Kim WB, Ryu JS, et al. 18F-Fluorodeoxyglucose uptake in thyroid from positron emission tomogram (PET) for evaluation in cancer patients: High prevalence of malignancy in thyroid PET incidentaloma. Laryngoscope 2005;115:1074-1078.
Yoon, Dae Young; Chang, Suk Ki; Choi, Chul Soon; Yun, Eun Joo MD. The Prevalence and Significance of Incidental Thyroid Nodules Identified on Computed Tomography. J Comput Assist Tomogr. 2008 Sep-Oct;32(5):810-5.
Ahmed Sammeer, Horton M. Karen, Jeffrey Brooke R Jr, et al. Incidental thyroid nodules on chest CT: Review of the literature and Management Suggestions. AJR 2010; 195:1066-1071.
Johnson A. Nathan MD, Tublin E. Mitchell, MD. Postoperative survillance of differentiated thyroid carcinoma: rationale, techniques and controversies. Radiology 2008;249:429- 444.
Agarwal MD, Barton F. Branstetter IV, Johnson Jonas T. Indications for PET/CT in the head and neck. Otolaryngol Clin N Am 41(2008):23-49.
Heston.T.F and Wahl R.L. Molecular imaging in thyroid cancer. Cancer imaging 2010; 10:1-7.
Hoang J, Lee W, Lee M, Johnson D & Farrell S. US Features of Thyroid Malignancy: Pearls and Pitfalls. RadioGraphics. 2007;27:847-865.
Quon Andrew, Fischbein I., Naney Mc Dougall Ross, et al. Clinical Role of F-FDG PET/CT in the management of squamous cell carcinoma of the head and neck and thyroid carcinoma. JNM 2007;48:58S-67S.
Zhuang Hongming, MD, PhD, Kumar Rakesh, MD, Mandel Susan MD, Alavi Abass, MD. Investigation of Thyroid, Head and Neck cancers with PET. Radiol Clin N Am 2004;42:1101- 1111.
Nam SY, Roh JL, Kim SS et al. Focal uptake of 18F-fluorodeoxyglucose by thyroid in patients with non-thyroidal head and neck cancers. Clin Endocrinol 2007;67:135- 139.
Kang BJ, O JH, Baik JH et al. Incidental thyroid uptake on F-18 FDG PET/CT: correlation with ultrasonography and pathology. Ann Nucl Med 2009;23:729-737.
Dirección General de Información en Salud (DGIS). Base de datos de defunciones 1979-2007. [en línea]: Sistema Nacional de Información en Salud (SINAIS). [México]: Secretaría de Salud. [Consulta: 06 septiembre 2011].