medigraphic.com

2000, Number 1

<< Back Next >>

Rev Med Hosp Gen Mex 2000; 63 (1)

The morphological spectrum of the tuberous sclerosis complex. Analysis of four necropsy cases

Serrano BLM, Durán PMA, Chávez MLG, Soriano RJ, Barba RM, Valenzuela EA, Olvera RJE

Language: Spanish
References: 14
Page: 12-17
PDF size: 397.17 Kb.


ABSTRACT

The authors analyze four cases of tuberous sclerosis whose most common findings were subependimal hamartomas and facial angiofibromas. Other findings were giant-cell subependimal astrocytomas, multiple cardiac rhabdomyomas, policystic kidneys, subungueal fibromas, hypocromic spots and renal and renal angiomyolipomas. The clinical and morphological presentation of tuberous sclerosis is heterogeneous. The authors use this review to illustrate the most important pathological features for diagnosis.


REFERENCES

  1. Powers JM, Horoupian DS. Central nervous system. In: Damjanov I, Linder J (eds). Anderson’s pathology. USA: Mosby, 1996; 2: 2693-2798.

  2. Louis DN, Deimling A. Hereditary tumor syndromes of the nervous system: Overview and rare syndromes. Brain Pathology 1995; 5: 145-51.

  3. Gomez MR. Phenotypes of the tuberous sclerosis complex with a revision of diagnostic criteria. Ann NY Acad Sci 1991; 615: 1-7.

  4. Albretch E. Ueber hamartome. Ver Dtsch Ges Pathol 1904; 7: 153-157.

  5. Bourneville D. Scléreuse tubéreuse des circonvolution cérebrales. Arch Neur Paris. 1880; 1: 81-91.

  6. Short MP, Richardson EP, Haines JL, Kiatkowski DJ. Clinical, neuropathological and genetic aspects of the tuberous sclerosis complex. Brain Pathology 1995; 5: 173-179.

  7. Eble JN. Angiomyolipoma of kidney. Sem Diag Pathol 1998; 15: 21-40.

  8. Risdon RA. Development, developmental defects and cystic diseases of the kidney. In: Heptinstall RH (ed). Pathology of the kidney. USA: Little Brown, 1992; 1: 93-167.

  9. Thomsen HS, Levine E, Meilstrup JW, Van-Slyke MA, Edgar KA, Barth JC, Hartman DS. Renal cystic diseases. Eur Radiol 1997; 7: 1267-1275.

  10. Bernstein J, Risdon RA, Gilbert-Barness E. Renal system. In: Gilbert-Barness E (ed). Potter’s pathology of the fetus and infant. USA: Mosby, 1997; 2: 863-935.

  11. Enzinger FM, Weiss SW. Rhabdomyoma. In: Enzinger FM, Weiss SW (eds). Soft tissue tumors. USA: Mosby, 1995: 523-37.

  12. Nir A, Tajik AJ, Freeman WK, Seward JB, Oxford KP et al. Tuberous sclerosis and cardiac rhabdomyoma. Am J Cardiol 1995; 76: 419-421.

  13. Kuramoto M, Kato M, Inoue Y. Pulmonary lymphangiomyomatosis with tuberous sclerosis and endolymphatic stromal myosis of the uterus. Nippon Kyobu Shikkan Gakkai Zasshi. 1996; 34: 322-326.

  14. Hasleton PS. Benign lung tumors and their malignant counterparts. In: Hasleton PS (ed). Spencer’s pathology of the lung. USA: McGraw-Hill, 1996: 875-986.




2020     |     www.medigraphic.com