2001, Number 4
<< Back Next >>
Rev Med Hosp Gen Mex 2001; 64 (4)
Congenital syphilis. Presentation of a case and review of the literature
Peña P, Cardiel-Marmolejo LE, Matamoros-Márquez M, Iturbide-Cruz LA, Ávalos-Martínez JL, Josefa GH
Language: Spanish
References: 25
Page: 240-245
PDF size: 148.95 Kb.
ABSTRACT
The syphilis is an infectocontagious disease caused by Treponema pallidum and its divided in first phase, second phase, latent and third phase. The neurosyphilis and congenital syphilis are considered individual forms, because the last one is transfer from the pregnant women to the infant across the transplacentary circulation. The mortality occurs in the 40% of the total infected newborn. Seventy five percent occurs in uterus and 25% a postnatal life. The clinical manifestations are different and can be asymptomatic disease or they can provoke the death in uterus or in a neonatal period. The clinical manifestation are considered early if they are presented before two years old, and later if they appears after this age. We describe a case of congenital syphilis in a newborn, male with a multisistemic affectation, diagnosticated by clinic historical, clinical manifestations and nontreponemal test positive in blood and cerebrospinal fluid, in the last one, we observed an increase of the number of cells. The treatment was with penicillin G a dose of 100,000 UI kg divided every 12 hours for 21 days, with adequate response and remission of disease.
REFERENCES
Murphy FK, Patamasucam P. Congenital syphilis. In: Holmes KK, Mardh PA, Sparling PF, Wiesner PFÑ (eds). Sexually transmitted diseases. New York: McGraw-Hill, 1984: 352-354.
Ingall D, Musher D. Syphilis. In: Remington JS, Klein JO (eds). Infectious diseases of the fetus and newborn infant. Philadephia: WB Sauders, 1983: 335-374.
ST Louis ME, Wesserheit JN. Elimination of syphilis in the United States. Science’s Compass, 1988; 281: 353-354.
Consolacion GS, Enrique MO, Milagros PR, Valiollah S. The resurgence of congenital syphilis: A cocaine-related problem. J Pediatr 1997; 130: 289-292.
Capella B, Tay ZJ, Del Muro R. Nociones elementales de microbiología médica. 2a ed. México: Méndez Editores, 1982: 233-424.
Morison JO. Patología fetal y neonatal. 3a ed. México: Editorial Pediátrica, 1972: 694.
Hellman LM, Pritchard JA. Obstetricia. México: Editorial Salvat, 1980: 43.
Williams F. Fisiología médica. 8a ed. México: Editorial Manual Moderno; 1982: 369-371.
Houssay BA. Fisiología humana. 5a ed. Argentina: Editorial El Ateneo, 1982: 653-656.
Moore KL. Embriología clínica. 2a ed. México: Interamericana, 1980: 98-120.
Berhman RE, Vaughan VC, Nelson. Tratado de pediatría. 12a ed. México: Interamericana, 1985: 753-7.
Santos JL. Enfermedades trasmitidas por contacto sexual. Infectología 1982; 2: 81-94.
Goldsmith MF. Sexually transmitted diseases may reverse the revolution. JAMA 1986; 255: 1665-1672.
Carrada BT. Lo que usted quiere saber sobre sífilis. Las enfermedades al día 1985; 101; 12-14.
Ulises RG, Luis CR, Gerardo LC, Apolinar CG, Nora PSC. Sífilis congénita. Arch Invest Ped Mex 2000; 2: 181-189.
Toni D. Syphilis. Pediat Rev 1999; 20: 160-165.
Lillian S. Noni E. MD: A syphilis perspective. Pediat Rev 1988; 19: 17-22.
Guadalajara JF. Cardiología. 3a ed. México: Méndez Cervantes, 1985: 17-22.
Virginia AM, Virginia S, Robert Y, Joseph GP, Deborah P, Timothy C. Contribution of long bone radiographs to the management of congenital syphilis in the newborn infant. Arch Pediatr Adolesc 1988; 152: 353-357.
Edeiken J. Roetgen diagnosis of diseases of bone. 3a ed. New York: McGraw-Hill, 1973: 776.
Azimi P. Enfermedades por espiroquetas. En: Behrman RE, Kliegman RM, Harbin AM (eds). Tratado de pediatría. 15a ed. México: McGraw-Hill, Interamericana, 1997: 1073-1078.
Vargas OA. Infecciones perinatales I. En: Games EJ, Palacios TJL (eds). Introducción a la pediatría. 5a ed. México: Méndez Editores; 1997: 251-252.
Feigin RD, Cherry JD. Tratado de infecciones en pediatría. 3a ed. México: Interamericana, 1983: 443-456.
Robbins SL. Patología estructural y funcional. España: Interamericana, 1975: 371-376.
Cloherty JP, Stark AR. Manual de cuidados neonatales. 3a ed. Barcelona: Masson, 1999: 346-355.