2012, Number 4
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Acta Med Cent 2012; 6 (4)
Polyarteritis nodosa
Bacallao MGC, Lima LCE, González AI
Language: Spanish
References: 10
Page:
PDF size: 286.37 Kb.
ABSTRACT
Polyarteritis nodosa is a rare disease whose incidence is estimated at 4 to 10 cases per million persons, and mainly affects men between 40 and 60 years of age. It is systemic necrotizing vasculitis that affects medium and small caliber muscular arteries, and secondarily arterioles and venules. The clinical manifestations are multiple with prevalence of fever and weight loss. The case of a 48-year-old man is reported. He was admitted for a febrile syndrome of “obscure origin”, with weight loss and muscle weakness. The diagnosis of polyarteritis nodosa was suspected, and it was confirmed in the histopathologic study by a muscle biopsy, associated with the finding of vascular retinopathy in the fundus examination. Early diagnosis and a treatment with steroids led to the successful evolution of the patient.
REFERENCES
Fauci SA, Langford AC, Sneller CM. The Vasculitis Syndromes. In: Fauci Braunwald K, Jameson Longp H. Harrisons Principles of Internal Medicine. 16 ed. New York: Mc Graw-Hill; 2006. p. 2002-14.
Beers HM, Porter SR, Jones VT, Kaplan LJ, Berkwits M. Vasculitis. En: El Manual Merck de diagnóstico y tratamiento. 11a ed. Madrid: Elseiver; 2006. p. 298-99.
Segovia Alarcón D, Aguado Gil A, Xutglá MC. Vasculitis. En: Farreras V, Rozman P. Medicina Interna [CD-ROM].14a ed. Madrid: Harcout; 2000. p. 1278-95
Benmett CJ, Plum F, Stone HJ. The Systemic Vasculitides. En: Cecil Medicina Interna [CD-ROM]. Philadelphia: Saunders; 2007. p. 274.
Guillevin L, Pagnoux C, Teixeira L. Polyarteritis nodosa and microscopic polyangiitis. In: Ball GV, Bridges SL. Vasculitis. 2nd ed. Oxford: Oxford University Press; 2008. p. 335-64.
Lugmani RA, Bacon PA. Assessment of vasculitis. In: Ball GV, Bridges eds. Vasculitis. 2nd ed. Oxford: Oxford University Press; 2008. p. 297-306.
Shields LBE, Rolf CM, Davis GJ, Hunsaker JC. Sudden and unexpected death in three cases of Ehler –Danlos síndrome type IV. Forensic Sci Int. 2010 Dec 15;203(1-3):1-2.
Ebert EC, Hagspiel KD, Nagar M, Schlesigner N. Gastrointestinal involvement in Polyarteritis nodosa. Clin Gastroenterol Hepatol. 2008;6(9):960-6.
Pettigrew HD, Teuber SS, Gershwin ME. Polyarteritis nudosa. Compr Ther. 2007;33(3):144-9.
Phullip R, Luqmani R. Mortality in systemic vasculitis: a systematic review. Clin Exp Rheumatol. 2008;Sep-Oct;26(5 Suppl 51):S94-104.