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2011, Number 1

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Rev Med MD 2011; 2.3 (1)

Fatty acids: cancer's friends or foes?

Meza-Guillen D, Martínez-García EA, Juárez-Rojas JG

Language: Spanish
References: 36
Page: 10-15
PDF size: 548.27 Kb.


ABSTRACT

Cancer is the uncontrolled cell growth, originated by diverse etiological factors. Fats have been contraindicated during pharmacological therapy against cancer, including some fatty acids that have proved beneficial results in intervention researches for the cancer treatment. The polyunsaturated fatty acids are associated to the significantly reduction on the incidence of proliferation of malignant melanomas, through the suppression of the cyclooxigenase-2 expression in tumors, the diminishment of AP-1 and RAS expression, the promotion of cancerous cell differentiation, malignant cell apoptosis and the decrease of cachexia. Within our population exists a deficient ingestion of these nutrients whether the cancer pathology develops or not.


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