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Colegio de Medicina Interna de México.

2012, Number 6

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Med Int Mex 2012; 28 (6)

Efficacy and efficiency of antibiotic treatment by clinical practice guidelines in patients hospitalized with acquired-community pneumonia

Pluma-Vázquez CA, Flores-Gómez L, Martínez-Bohórquez C, Torres-Benítez JM

Language: Spanish
References: 20
Page: 554-559
PDF size: 190.30 Kb.


ABSTRACT

Background: Community acquired pneumonia (CAP) is a common condition in which antibiotic treatment thus remains empirical. The lack of adherence to clinical practice guidelines (CPG) leads to the use of alternative schemes without knowing the efficacy or efficiency of such schemes.
Objetive: To evaluate the efficacy and efficiency of empirical antibiotic regimens for hospital treatment of CAP.
Material and methods: observational, descriptive, retrospective and cross 62 patients diagnosed with CAP hospitalized in internal medicine, divided into 2 study groups in relationship to antibiotic therapy or not, used according to the CPG. Both compared the efficacy and efficiency.
Results: Of the 62 patients, 44% were treated with antibiotic regimens based on clinical practice guidelines and 55% with alternate antibiotic regimens, not covered by the guidelines. The efficacy for both regimens was 82%, being higher for the GPC-based schemes for other alternate schemes, 86% vs 79% (p <0.51), but efficiency was observed for CPG-based schemes.
Conclusions: Both GPC schemes based antibiotics, such as alternative antibiotic regimens, not recognized in a directory have the same ability to achieve healing (efficacy), but there is greater efficiency with the use of GPC-based schemes.



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