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2012, Number 2

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Rev Med Inst Mex Seguro Soc 2012; 50 (2)

Acute leukemia frequency observed in a reference hospital

González-Salas WM, Olarte-Carrillo I, Gutiérrez-Romero M, Montaño-Figueroa EH, Martínez-Murillo C, Ramos-Peñafiel CO

Language: Spanish
References: 20
Page: 167-171
PDF size: 60.02 Kb.


ABSTRACT

Objective: to compare the frequency of acute leukemia in two periods of study in a reference Hospital at Mexico City.
Methods: it was an observational study. There were registered 250 cases with the morphology diagnostic criterion of acute leukemia.
Results: 63 cases versus 92 of acute lymphoid leukemia (ALL) and 16 versus 79 acute myeloid leukemia (AML) of 1990-1992 versus 2008-2009 respectively was observed; corresponding to 62 % in total of ALL in both periods and 38 % of AML. The ALL was the most frequent variant (62 % versus 38 %). The median age was 26 years, male 52 %. It showed a significant increase in the number of admissions in the period of 2008-2009 and acute promyelocytic leukemia also showed an increase (p = 0.001).
Conclusions: acute leukemia is the main cause of admission, mortality and morbidity. Our study differs slightly from the literature; the leukemia that diagnostic with major frequency was the acute lymphoid leukemia increasing his number in the period of 2008- 2009. The significant rise due to an increase use of new diagnostic tools such as the flow cytometry and molecular biology.


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