2012, Number 5
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Rev Med Inst Mex Seguro Soc 2012; 50 (5)
Clear cells cervical adenocarcinoma in a girl no exposed to dietiletilbestrol
Romero-Durán E, Chávez-Bravo NC, García-Rodríguez AS
Language: Spanish
References: 18
Page: 549-552
PDF size: 107.17 Kb.
ABSTRACT
Background: the clear cell adenocarcinoma (CCA) in cervix is a
rare disease. It represents only 2 to 7% of whole adecocarcinomas
of cervix. Its histological pattern seems identical to their counterparts
elsewhere in the female genital tract, including the vagina,
endometrial and ovary. The CCA is constituted by cells with a
clear cytoplasm in tack that are arranged in a solid pattern, tubulocystic,
papillary, or mixed.
Clinical case: an eleven year old girl with sporadic and intermittent
transvaginal bleeding, and who felt in severe anemia
due to hiperpolimenorrea treated with athinyl estradiol desogestrel
was attended. She had not history of exposition in
utero to diethyletilbestrol. Hysteroscopy showed an ectocervical
exophytic lesion in a barrel of 7 × 3 × 3 cm, located predominantly
in the posterior lip. A frozen section of the lesion was
reported as a poorly differentiated malignant tumor compatible
with cervical carcinoma. She underwent to simple trachelectomy.
Conclusions: diagnostic difficulty was the age of the patient and
the lack exposition in utero to DES, the differential diagnosis
included the age group tumors and rhabdomyosarcoma botryoides
and extragonadal endodermic origen with papillary and reticular
pattern. Another was a metastatic CCA.
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