2012, Number 5
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Rev Med Inst Mex Seguro Soc 2012; 50 (5)
Changes in maturation index and vaginal dryness in Mexican postmenopausal women who
Carranza-Lira S, Amador-Pérez C, MacGregor-Gooch AL, Estrada-Moscoso I
Language: Spanish
References: 10
Page: 537-540
PDF size: 151.64 Kb.
ABSTRACT
Background: it is known that vitamin D increases the population
of superficial cells, so the objective of the present work was to
evaluate the effect in Mexican postmenopausal women who
were using or not oral calcitriol.
Methods: postmenopausal women with vaginal dryness that received
at random: calcium 500 mg orally e/24 h or calcitriol
0.25 μg e/24 h during two months. At the beginning of treatment
and at two months a vaginal Pap smear was performed. The
maturation index was determined and the estrogenic value was
calculated. Vaginal dryness was evaluated using an analog
visual scales and vaginal by the moistening of a pH test strip.
Student’s t test was used for statistical analysis.
Results: 23 postmenopausal women were studied and divided
as follows: group I (calcium) = 11 women and group II (calcitriol)
= 12 women. In the analyzed parameters only the average of
superficial cells was significantly greater at the end of treatment
in the calcitriol group.
Conclusion: calcitriol use increased the average of superficial
cells in vaginal cytology, whereas didn’t modify vaginal dryness.
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