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2012, Number 4

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Rev Med Inst Mex Seguro Soc 2012; 50 (4)

Solanum torvum toxicological evaluation on microorganism and sperm cells

Domínguez-Odio A, Puente-Zapata E, Pérez-Andrés IY, Salas-Pérez H

Language: Spanish
References: 35
Page: 363-370
PDF size: 112.49 Kb.


ABSTRACT

Objective: to evaluate the toxic effect of an aqueous extract of Solanum torvum on microorganisms responsible for genitourinary infections as well as the adverse effects on sperm cells.
Methods: it was determined the microbial toxicity of a freeze-dried aqueous extract (obtained from the leaves and stems of Solanum torvum), against wild strains of Escherichia coli, Neisseria gonorrhoeae and Candida albicans, using the test of poisoning in culture medium at concentrations of 50, 100 and 200 mg/mL. The responsewas evaluated with the colony diameter (mm). Then, it was evaluated the toxicological potential on male reproductive system using the testing of morphology of the sperm head in NMRI mice.
Results: the Solanum torvum had bacteriostatic antibacterial activity. There were not observed alterations in quantity and quality characteristics in semen with the oral and doses used of 500, 1000 y 2000 mg/kg of weight.
Conclusions: the Solanum torvum under described, inhibits the growth of bacteria and produces no disturbance on semen quality in the species studied.



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