Alonso-Rodríguez D, Moreno-Téllez E, Alarcón-Martínez Y, Pedroso-Filiberto E

Language: Spanish
References: 11
Page: 345-347
PDF size: 49.97 Kb.

ABSTRACT

The acute arterial hypertension is an entity of unquestionable pronostic value, due to others factors like dislipidemia, and it plays a main role in the origin of the atherosclerotic process; the cytoquines freed during this process increased C reactive protein levels in blood. We studied a group of hypertense adult in order to determine lipid and C reactive protein levels in serum as a marker of inflammation. The results shown high levels of lipid in serum in 100 % of the patients, the highest levels of C reactive protein corresponded with the highest levels of total cholesterol and LDL oxidized, it was suggested as a atherosclerotic disease risk.

REFERENCES

1. Álvarez CA. Las tablas de riesgo cardiovascular. Una revisión crítica. México: Medifarm 2001;11(3):121-139.

2. Stein JH, Rosenson RS. Lipoprotein Lp(a) excess and coronary heart disease. Arch Intern Med 1997;157(11): 1170-1176.

3. Ross R. The pathogenesis of atherosclerosis: a perspective from the 1990s. Nature 1993;362(6423):801-809.

4. Liuzzo G, Biasucci LM, Gallimore JR, Grillo RL, Rebuzzi AG, Pepys MB, et al. The prognostic value of C-reactive pro-tein and serum amyloid A protein in severe unstable angina. N Engl J Med 1994;331(7):417-424.

5. Pepys MB, Baltz ML. Acute phase proteins with special reference to C reactive protein and related proteins (pentaxins) and serum amyloid A protein. Adv Immunol 1983;34:141-212.

6. Hansson G, Stemme V, Yokota T. Cytokines and the cardiovascular system. En: Remick DG, Friedland JS, editores. Citokines. Nueva York: Marcel Decker; 1997. p. 507- 518.

7. Mehta JL, Saldeen TG, Rand K. Interactive role of infection, inflammation and traditional risk factors in ahterosclerosis and coronary artery disease. J Am Coll Cardiol 1998;31 (16):1217-1225.

8. Schultz DR, Arnold PI. Properties of four acute phase proteins: C-reactive protein, serum amyloid A protein, alpha 1-acid glycoprotein, and fibrinogen. Semin Arthritis Rheum 1990;208(3):129-147.

9. Liuzzo G, Biasucci LM, Gallimore JR, Grillo RL, Rebuzzi AG, Pepys MB, et al. The prognostic value of C-reactive protein and serum amyloid A protein in severe unstable angina. N Engl J Med 1994;331(7):417-424.

10. Liu ML, Ylitalo JK, Vakkilainen J. et al. Susceptibility of LDL to oxidation in vitro and antioxidant capacity in familial combined Hiperlipidemia: comparation of patients with different lipìd phenotypes. Ann Med 2002;34(1):48-54.

11. DeBeer FC, Hind CR, Fox KM, Allan RM, Maseri A, Pepys MB. Measurement of serum C-reactive protein concentration in myocardial ischemia and infarction. Br Heart J 1982;47(3):239-243.