Arce-Rosas JI, García-Castro JA

Language: Spanish
References: 14
Page: 120-123
PDF size: 1153.93 Kb.

ABSTRACT

22 year old male diagnosed with AIDS in stage C3 presents sub-acute and persistent cephalalgia, nausea, vomit, weight loss and diminished visual acuity. Diagnosis of meningeal criptococcosis is made, and antifungal 14 day treatment with amphotericin B and fluconazole is administered. Forward to this, maintenance treatment with only fluconazole continues. All symptoms subside except to the diminished visual acuity. A month after being checked out from the hospital he is admitted again in account of generalized tonic – clonic seizures. Cranial CT scan is performed, in which new frontal masses are shown. Antibodies for Toxoplasma gondii are negative; adenosine deaminase in cerebral spine fluid is 15 U/L. In absence of relapse of meningeal criptococcosis or other nervous infection, antituberculous treatment is administered, resulting in clinical improvement in the patient. Progression of Human Immune Deficiency virus leads to recurrent opportunistic infections, most frequently criptococcosis and tuberculosis (TB) in any of their presentations. These two entities affect Central Nervous System and share many clinical manifestations, which is why in clinical suspicion of one of them the other has to be taken into account as differential diagnosis.

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