2012, Number 2
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Evid Med Invest Salud 2012; 5 (2)
Post-thrombolysis mortality versus angioplasty in patients with acute coronary ischemic syndrome admitted to the intensive care unit at the Hospital ISSSTE Zaragoza
Raymundo ACA, Navarrete AH, Terrazas LVM
Language: Spanish
References: 24
Page: 55-58
PDF size: 152.96 Kb.
ABSTRACT
Acute coronary syndromes are a public health problem in the world and in Mexico is one of the leading causes of death in the adult population. The objective of this study was to demonstrate that angioplasty is the treatment offering better coronary reperfusion and survival in patients with acute coronary syndrome. A retrospective, observational and comparative study was conducted. We included a total of 91 patients: 34 (37.36%) women and 57 (62.63%) men, 67 subjects had infarction with ST segment elevation, eight without ST segment elevation and 16 had unstable angina. Thrombolysis treatment was applied to 57 patients and angioplasty to 34. There were four deaths; three of these patients received thrombolytic therapy and one angioplasty treatment. The main cause of death was cardiogenic shock. There was a value of p = 0.571 and OR (Odds Ratio) of 1.92 in death of patients treated with thrombolysis. Therefore, for this study angioplasty is the treatment offering lower mortality, greater myocardial reperfusion and better quality of life.
REFERENCES
Martínez SCR. Síndromes isquémicos coronarios agudos. 2a ed. México: Intersistemas; 2010: 1-47.
Guías de Práctica Clínica de la Sociedad Europea de Cardiología (ESC). Manejo del infarto agudo de miocardio en pacientes con elevación persistente del segmento ST. Rev Esp Cardiol 2009; 62 (3): e1-e47.
Boersma E, Mercado N, Poldermans D et al. Acute myocardial infarction. Lancet 2003; 361: 847.
Thygessen K, Alpert JS, White HD. Universal definition of myocardial infarction. Eur Heart J 2007; 28: 252-238.
Bonow RO, Braunwald E, Mann DL. Braunwald’ s heart disease. A textbook of cardiovascular medicine. 9th ed. Philadelphia, PA: Elsevier Saunders; 2011: 1207-1293.
Goodman L, Gilman A, , Brunton LL, , Lazo JS, Parker KL. Goodman and Gilman´s the pharmacological basis of therapeutics. New York: McGraw-Hill; 2007.
EUROASPIRE II Study Group. Lifestyle and risk factor management and use of drug therapies in coronary patients from 15 countries; principal results from EUROASPIRE II Euro Heart Survey Programme. Eur Heart J 2001; 22: 554-572.
Ribichi F, Wijns W. Acute myocardial infarction, reperfusion treatment heart. 2002; 164 (9): 1285-1290.
Jneid H, Anderson JL, Wright RS. 2012 ACCF/AHA Focused Update of the Guideline for the Management of Patients With Unstable Angina/Non-ST-Elevation Myocardial Infarction (Updating the 2007 Guideline and Replacing the 2011 Focused Update): A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 2012; 60 (7): 645-681.
RENASICA II, Registro Mexicano de Síndromes Coronarios Agudos. Arch Cardiol Mex 2005; 75: S6-S19.
Corbalan R, Prieto JC, Chávez MD, Cumsille F, Nazzal C, Krucoff M. Bedside markers of coronary artery patency and short-term prognosis of patients with acute myocardial infarction and thrombolysis. Am Heart J 1999; 138, 533-599.
Sheehan FH, Braunwald E, Canner P, Dodge HT, Gore J, Van Natta P et al. The effect of intravenous thrombolytic therapy on left ventricular function, a report on tissue-type plasminogen activator and streptokinase from the thrombolysis in myocardial infarction (TIMI phase I) trial. Circulation 1987; 75: 817-829.
Davies M, Woolf N, Robertson W. Pathology of acute myocardial infarction with particular reference to occlusive coronary thrombus. Br Heart 1976; 38: 659-664.
Rentrop P, Blanke H, Karsh K, Kaiser H, Kostering H, Leitz K. Selective intracoronary thrombolysis in acute myocardial infarction and unstable angina pectoris. Circulation 1981; 63: 307-317.
Ganz W, Ninomiya K, Hashida J, Fisebein M, Buchbinder N, Marcus H et al. Intracoronary thrombolysis in acute myocardial infarction: experimental background and clinical experience. Am Heart J 1981: 102: 1145-1149.
Hartzler G, Rumerrford B, Mcconahay D, Johnson W, McAllister B, Gura G et al. Percutaneous transluminal coronary angioplasty with and without thrombolytic therapy for treatment of acute myocardial infarction. Am Heart J 1983; 106: 965-973.
Zaijlstra F, DeBoer M, Hoornje, Reiffers S, Reiber J. A comparison of immediate coronary angioplasty with intravenous streptokinase in acute myocardial infarction. N Engl J Med 1993; 328: 680-684.
Akhras F, Abu Ousa A, Swann G, Duncan H, Chamsi-Pasha H, Jabba H. Primary coronary angioplasty or intravenous thrombolysis for patients with acute myocardial infarction? Acute and late follow-up results in a new cardiac Unit. J Am Coll Cardiol 1997; (suppl): A235-236.
Weaver W, Simes R, Betriu A, Grines C, Zaijlstra F, Garcia E et al. Comparison of primary coronary angioplasty and intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review. JAMA 1997; 278: 1093-1098.
Grupo de Trabajo de la Sociedad Europea de Cardiología (ESC). Guías de Práctica Clínica de la Sociedad Europea de Cardiología (ESC). Manejo del infarto agudo de miocardio en pacientes con elevación persistente del segmento ST. Rev Esp Cardiol 2009; 62 (3): e1-e47.
Focused updates ACC/AHA Guidelines for the Management of patients with ST elevation myocardial infarction (updating the 2004, guideline and 2007 focused update) and ACC/AHA/SCAI guidelines on percutaneous coronary intervention (updating the 2005 guideline and 2007, focused update): A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation 2009; 120: 2271-2306.
Bjorklund E, Lindahl B, Stenestrand U, Swann E, Dellborg M, Pehersson K et al. Outcome of ST elevation myocardial infarction treated with thrombolysis in the, unselect population is vastly different from samples of eligible patients in large scale clinical trial. Am Heart J 2004; 148: 566-573.
Ribeiro E, Silva L, Carneiro, D’oliveira L, Gasquez A, Amino J et al. Randomized trial of direct coronary infarction results from single trial. J Am Coll Cardiol 2001.
García RC, Díaz BC. Acute myocardial infarction with ST elevation: primary PTCA for everyone, or will thrombolysis remain for long time. Rev Colomb Cardiol 2005; 12 (4): 151-156.