2007, Number 1
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Rev Educ Bioquimica 2007; 26 (1)
Muerte apoptótica en drosophila melanogaster y en vertebrados superiores
Vázquez MO, Morales TV, Díaz MM
Language: Spanish
References: 16
Page: 11-17
PDF size: 53.89 Kb.
ABSTRACT
Programmed cell death or apoptosis is a crucial
mechanism to eliminate damaged or infected cells, as
well as cells that disappear during the embryonic
development. Failure in the coordination of this process
results in pathological consequences such as cancer,
cardiac insufficiency, autoimmune diseases and
infertility. Apoptosis is a phenomenon conserved along
the evolutionary progression. The experimental studies
in genetically less complex organism than mammals,
have given insights into the molecules and events related
to apoptotic pathways. We offer an overview about
the biological importance of apoptosis, and point out
that the most relevant information about this process
is based in basic research done in more accessible
organisms.
REFERENCES
Danial NN, Korsmeyer SJ (2004) Cell death: critical control points. Cell 116: 205-219.
Twomey C, McCarthy JV (2005) Pathways of apoptosis and importance in development. J Cell Mol Med 9: 343- 359.
Bowie AG, Zhan J, Marshall WL (2004) Viral appropriation of apoptotic and NF-kappa B signaling pathways. J Cell Biochem 91: 1099-1108.
Giannetti L, Consolo U, Magnoni C, Muzio L (2004) Apoptosis: Escaping strategies in human skin cancer. Oncol Rep Feb 11: 401-5.
Hardwick JM (1998) Viral interference with apoptosis. Semin Cell Dev Biol 9: 339-49.
van den Eijnde SM, Boshart L, Baehrecke EH, De Zeeuw CI, Reutelingsperger CPM, Vermeij-Keers C (1998) Cell surface exposure of phosphatidylserine during apoptosis is phylogenetically conserved. Apoptosis 3: 9-16.
Yan N, Shi Y (2005) Mechanisms of apoptosis through structural biology. Annu Rev Cell Dev Biol 21: 35- 56.
Kornbluth S, White K (2005) Apoptosis in Drosophila: neither fish nor fowl (nor man, nor worm). J Cell Sci. 118:1779-87.
Schafer Z, Kornbluth S (2006) The apoptosome: physiological, developmental, and pathological modes of regulation. Develop Cell 10: 549-561.
Cashio P, Lee TV, Bergman A (2005) Genetic control of programmed cell death in Drosophila melanogaster. Semin Cell Dev Biol 16: 225-235.
Martin DN, Baehrecke EH (2003) Caspases function in autophagic programmed cell death in Drosophila. Development 131: 275-284.
Baehrecke EH (2003) Autophagic programmed cell death in Drosophila. Cell Death and Differentiation 10: 940- 945.
Abrams JM, White K, Fessler LI, Steller H (1993) Programmed cell death during Drosophila embryogenesis. Development 117: 29-43.
Milán M, Campuzano S, García-Bellido A (1997) Developmental parameters of cell death in the wing disc of Drosophila. Proc Natl Acad Sci USA 94: 5691- 5696.
Brachmann CB, Cagan RL (2003) Patterning the fly eye: the role of apoptosis. TIGS 19: 91-96.
Ferraro E, Corvaro M, Cecconi F (2003) Physiological and pathological roles of Apaf1 and the apoptosome. J Cell Mol Med. 7:21-34.