medigraphic.com
ISSN 2007-2783 (Print)
Órgano Oficial del Instituto Científico Pfizer

2012, Number 2

<< Back

Residente 2012; 7 (2)

Enriquecimiento ambiental y drogas de abuso

Páez MN

Language: Spanish
References: 24
Page: 76-81
PDF size: 39.89 Kb.


ABSTRACT

Environmental enrichment is a preclinical model that pretends mimic positive life conditions. This model has been able to reduce the progression and the symptoms of different central nervous system disorders. Recent investigations have shown that environmental enrichment plays an important role in the vulnerability in the intake and reinforce effects of abused drugs, as well as in the reduction of addiction-related effects. At the clinical level pharmacological and psychological approaches in cessation programs are used; however it is still necessary to look for new strategies that help to increase the success of these programs. Environmental enrichment studies pretend to extend our knowledge about the addiction process and to be a useful tool in the design of new therapeutical approaches for addiction treatment.


REFERENCES

  1. NIDA (National Institute on Drug Abuse). Drugs, Brains and Behavior. The Science of Addiction. NIDA, 2010.

  2. Secretaría de Salud. Encuesta Nacional de Adicciones. México, 2008

  3. Madras BK. Introduction. In: Madras BK, Colvis CM, Pollock JD, Rutter JL, Shurtleff D and von Zastrow M, eds. Cell Biology of Addiction. New York: Cold Spring Harbor Laboratory Press; 2006: 1-12

  4. Huerta-Rivas AG, Cruz SL. Adicciones y memoria. El Residente 2011; 6: 69-77.

  5. Volkow ND, Fowler JS, Wang GJ, Baler R, Telang F. Imaging dopamine’s role in drug abuse and addiction. Neuropharmacology 2009; 56: 3–8.

  6. Volkow ND. Imaging the Addicted Brain: From Molecules to Behavior . J Nucl Med 2004; 45(11): 13N-16N, 19N-20N, 22N passim

  7. Morgan D, Grant KA, Gage HD, Mach RH, Kaplan JR, Prioleau O, Nader SH, Buchheimer N, Ehrenkaufer RL, Nader MA. Social dominance in monkeys: dopamine D2 receptors and cocaine self-administration. Nat Neurosci. 2002; 5(2): 169-174.

  8. NIDA (National Institute on Drug Abuse). Principles of drug addiction treatment. A research-based guide. National Institute on Drug Abuse, 2009.

  9. Nithianantharajah J, Hannan AJ. Enriched environments, experience-dependent plasticity and disorders of the nervous system. Nat Rev Neurosci 2006; 7(9): 697-709.

  10. van Praag H, Kempermann G, Gage FH. Neural consequences of environmental enrichment. Nat Rev Neurosci 2000; 1(3): 191-198.

  11. Laviola G, Hannan AJ, Macrì S, Solinas M, Jaber M. Effects of enriched environment on animal models of neurodegenerative diseases and psychiatric disorders. Neurobiol Dis 2008; 31(2): 159-168.

  12. Renoir T, Pang TY, Hannan AJ. Effects of environmental manipulations in genetically targeted animal models of affective disorders. Neurobiol Dis 2012; doi:10.1016/j.nbd.2012.04.003

  13. Solinas M, Thiriet N, Chauvet C, Jaber M. Prevention and treatment of drug addiction by environmental enrichment. Prog Neurobiol 2010; 92(4): 572-592.

  14. Bardo MT, Klebaur JE, Valone JM, Deaton C. Environmental enrichment decreases intravenous self-administration of amphetamine in female and male rats. Psychopharmacology (Berl) 2001; 155(3): 278-284.

  15. Puhl MD, Blum JS, Acosta-Torres S, Grigson PS. Environmental enrichment protects against the acquisition of cocaine self-administration in adult male rats, but does not eliminate avoidance of a drug-associated saccharin cue. Behav Pharmacol 2012; 23(1): 43-53

  16. Deehan GA Jr, Palmatier MI, Cain ME, Kiefer SW. Differential rearing conditions and alcohol-preferring rats: consumption of and operant responding for ethanol. Behav Neurosci 2011; 125(2): 184-193.

  17. El Rawas R, Thiriet N, Lardeux V, Jaber M, Solinas M. Environmental enrichment decreases the rewarding but not the activating effects of heroin. Psychopharmacology (Berl) 2009; 203(3): 561-570.

  18. Xu Z, Hou B, Gao Y, He F, Zhang C. Effects of enriched environment on morphine-induced reward in mice. Exp Neurol 2007; 204(2): 714-719.

  19. Solinas M, Thiriet N, El Rawas R, Lardeux V, Jaber M. Environmental enrichment during early stages of life reduces the behavioral, neurochemical, and molecular effects of cocaine. Neuropsychopharmacology 2009; 34(5): 1102-1111.

  20. Bezard E, Dovero S, Belin D, Duconger S, Jackson-Lewis V, Przedborski S, Piazza PV, Gross CE, Jaber M. Enriched environment confers resistance to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and cocaine: involvement of dopamine transporter and trophic factors. J Neurosci 2003; 23(35): 10999-11007.

  21. Green TA, Cain ME, Thompson M, Bardo MT. Environmental enrichment decreases nicotine-induced hyperactivity in rats. Psychopharmacology (Berl) 2003; 170: 235-241.

  22. Chauvet C, Lardeux V, Goldberg SR, Jaber M, Solinas M. Environmental enrichment reduces cocaine seeking and reinstatement induced by cues and stress but not by cocaine. Neuropsychopharmacology 2009; 34(13): 2767-2778

  23. Thiel KJ, Sanabria F, Pentkowski NS, Neisewander JL. Anti-craving effects of environmental enrichment. Int J Neuropsychopharmacol 2009; 12(9):1151-1156.

  24. Dell D, Hopkins C. Residential volatile substance misuse treatment for indigenous youth in Canada. Subst Use Misuse 2011; 46(Suppl 1): 107-113.




2020     |     www.medigraphic.com