medigraphic.com
ISSN 1025-0255 (Electronic)

2012, Number 4

<< Back Next >>

AMC 2012; 16 (4)

Antimicrobial prophylaxis in orthopedics

Álvarez LA, García LY

Language: Spanish
References: 35
Page: 452-462
PDF size: 195.91 Kb.


ABSTRACT

Background: postoperative infection is a complication with a high social and economic cost; sometimes it may cause the death of the patient, therefore the importance of preventing and treating this disease in time.
Objective: to assess the behavior and results of the prophylactic antimicrobial therapy in a basic working group.
Method: a descriptive observational study was conducted in the University Hospital Manuel Ascunce Domenech, from December 2009 to July 2010. Constituted the sample of the study 93 patients, prophylactic antimicrobial therapy was applied.
Results: the average age was 43.5 years. Female-male sex relation from 2 to 1, 4 were observed. The method was mostly applied in 28 patients with closed fractures which internal fixation was performed. Cefazolin was the most widely used antimicrobial, 35 patients presented one or more risk factors associated with infection, one of them developed postoperative infection.
Conclusions: the prophylactic antimicrobial therapy is effective in the prevention of postoperative infection.


REFERENCES

  1. Tunger O, Karakaya Y, Cetin CB, Dinc G, Borand H. Rational antibiotic use. J Infect Dev Ctries. 2009; 3(2):88-93.

  2. Zywiel MG, Johnson AJ, Stroh DA, Martin J, Marker DR. Prophylactic oral antibiotics reduce reinfection rates following two-stage revision total knee arthroplasty. Int Orthop. 2011; 35(1):37-42.

  3. Mammel J, Kmet L. Perioperative antibiotic administration in orthopaedic trauma: a quality assurance project. Orthop Nurs. 2010; 29(2):77-83.

  4. Assor M. Noncemented total knee arthroplasty with a local prophylactic anti-infection agent: a prospective series of 135 cases. Can J Surg. 2010; 53(1):47-50.

  5. Braxton CC, Gerstenberger PA, Cox GG. Improving antibiotic stewardship: order set implementation to improve prophylactic antimicrobial prescribing in the outpatient surgical setting. J Ambul Care Manage. 2010; 33(2):131-40.

  6. Burnett RS, Aggarwal A, Givens SA, McClure JT, Morgan PM. Prophylactic antibiotics do not affect cultures in the treatment of an infected TKA: a prospective trial. Clin Orthop Relat Res. 2010; 468(1):127-34.

  7. Calise F, Capussotti L, Caterino S, Delitala A, Terrazzi P. Perioperative antibiotic prophylaxis in adults. Outline of the principal recommendations. National reference guidelines. Minerva Anestesiol. 2009; 75(9):543-7.

  8. Cavanaugh DL, Berry J, Yarboro SR, Dahners LE. Better prophylaxis against surgical site infection with local as well as systemic antibiotics. An in vivo study. J Bone Joint Surg Am. 2009; 91(8):1907-12.

  9. Gillespie WJ, Walenkamp GH. Antibiotic prophylaxis for surgery for proximal femoral and other closed long bone fractures. Cochrane Database Syst Rev. 2010; 17; 3:CD000244.

  10. Rico Licona C, Cariño Ortega C. The paradigm of prophylactic antibiotic therapy in orthopedic surgery. Acta Ortop Mex. 2009; 23(3):137-41.

  11. Meehan J, Jamali AA, Nguyen H. Prophylactic antibiotics in hip and knee arthroplasty. J Bone Joint Surg Am. 2009; 91(10):2480-90.

  12. de Beer J, Petruccelli D, Rotstein C, Weening B, Royston K. Antibiotic prophylaxis for total joint replacement surgery: results of a survey ofCanadian orthopedic surgeons. Can J Surg. 2009; 52(6):229-34.

  13. Abubaker AO. Use of prophylactic antibiotics in preventing infection of traumatic injuries. Dent Clin North Am. 2009; 53(4):707-15.

  14. Marek CL, Ernst EJ. The new American Academy of Orthopedic Surgeons' recommendations regarding antibiotic prophylaxis: where's the evidence? Spec Care Dentist. 2009; 29(6):229-31.

  15. Metcalf R, Johnson R. Surgical care improvement project and the orthopaedic patient. Orthop Nurs. 2009; 28(5):227-31.

  16. Sumiyama Y, Arima Y. Surgical site infection (SSI) and postoperative infection. Masui. 2010; 59(1):36-45.

  17. Morris AM, Howie S. Recommendations for antibiotics in patients with joint prosthesis are irresponsible and indefensible. J Can Dent Assoc. 2009; 75(7):513-5.

  18. Randelli P, Evola FR, Cabitza P, Polli L, Denti M. Prophylactic use of antibiotic-loaded bone cement in primary total knee replacement. Knee Surg Sports Traumatol Arthrosc. 2010; 18(2):181-6.

  19. Cole LM. Prophylactic antibiotics: What's your game plan?. Nurs Manage. 2010; 41(4):46-7.

  20. Moriarty TF, Schlegel U, Perren S, Richards RG. Infection in fracture fixation: can we influence infection rates through implant design?. J Mater Sci Mater Med. 2010; 21(3):1031-5.

  21. Falagas ME, Alexiou VG, Peppas G, Makris GC. Do changes in antimicrobial resistance necessitate reconsideration of surgical antimicrobial prophylaxis strategies? Surg Infect (Larchmt). 2009; 10(6):557-62.

  22. Hadzikadic-Gusic L, Agarwal S. Current prophylactic perioperative antibiotic guidelines in trauma: a review of the literature and outcome data. Bosn J Basic Med Sci. 2009; 9:46-53.

  23. Stefánsdóttir A, Robertsson O, W-Dahl A, Kiernan S, Gustafson P. Inadequate timing of prophylactic antibiotics in orthopedic surgery. We can do better. Acta Orthop. 2009; 80(6):633-8.

  24. Freeman AF, Holland SM. Antimicrobial prophylaxis for primary immunodeficiencies. Curr Opin Allergy Clin Immunol. 2009; 9(6):525-30.

  25. Lee H, Jung D, Yeom JS, Son JS, Jung SI. Evaluation of ceftriaxone utilization at multicenter study. Korean J Intern Med. 2009; 24(4):374-80.

  26. Jiménez-Álvarez A, Acosta-Gutiérrez P, León-Govea MA, Contreras-Mendoza EJ, Millán-Guerrero RO. Antibiotic therapy frequency in hospitalised patients and associated risk factors. Rev Salud Publica (Bogota). 2009; 11(2):247-55.

  27. O'Toole JE, Eichholz KM, Fessler RG. Surgical site infection rates after minimally invasive spinal surgery. J Neurosurg Spine. 2009;11(4):471-6.

  28. Hsu C, Cheng SH. Practice guideline adherence and health care outcomes--use of prophylactic antibiotics during surgery in Taiwan. J Eval Clin Pract. 2009; 15(6):1091-6.

  29. Kim DH, Spencer M, Davidson SM, Li L, Shaw JD. Institutional prescreening for detection and eradication of methicillin-resistant Staphylococcus aureus in patients undergoing elective orthopaedic surgery. J Bone Joint Surg Am. 2010; 92(9):1820-6.

  30. Kuong EE, Ng FY, Yan CH, Fang CX, Chiu PK. Antibiotic prophylaxis after total joint replacements. Hong Kong Med J. 2009; 15(6):458-62.

  31. Alexiou VG, Ierodiakonou V, Peppas G, Falagas ME. Antimicrobial prophylaxis in surgery: an international survey. Surg Infect (Larchmt). 2010; 11(4):343-8.

  32. Prokuski L. Prophylactic antibiotics in orthopaedic surgery. J Am Acad Orthop Surg. 2008; 16(5):283-93.

  33. Langer M. Perioperative antibiotic prophylaxis in adults: the 2008 update of the Italian Guidelines. How can we as anesthetists contribute to the reduction of surgical site infections?. Minerva Anestesiol. 2009; 75(9):540-2.

  34. Thompson CA. Surgical antimicrobial prophylaxis improves through teamwork. Am J Health Syst Pharm. 2009; 66(17):1516-7.

  35. Harness NG, Inacio MC, Pfeil FF, Paxton LW. Rate of infection after carpal tunnel release surgery and effect of antibiotic prophylaxis. J Hand Surg Am. 2010; 35(2):189-96.




2020     |     www.medigraphic.com