2008, Number 4
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Rev Educ Bioquimica 2008; 27 (4)
El origen de la acidez en la glucolisis anaerobia
Mendoza MA
Language: Spanish
References: 12
Page: 111-118
PDF size: 90.82 Kb.
ABSTRACT
When anaerobic metabolism of glucose is dealt in many
courses of Biochemistry it is affirmed that the final
product of such a process is lactic acid. However, the
evidence points out that lactate dehydrogenase produces
lactate and not lactic acid. On the other hand, it has
been shown that when glucose is catabolized
anaerobically in mammalian organisms, acidity is
produced. But, which is the origin of hydrogen ions
during anaerobiosis? One trend holds that the hydrolysis
of ATP is the source of hydrogen ions, but another trend
sustains that, since electroneutrality has to be preserved
in any condition, ionization of water allows to keep
equilibrium between cations and anions when anion
concentration is increased as occurs when large
quantities of lactate are produced.
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