2009, Number 3
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Rev Educ Bioquimica 2009; 28 (3)
La capacidad antioxidante total. Bases y aplicaciones
Quintanar EMA. Calderón S JV
Language: Spanish
References: 16
Page: 89-101
PDF size: 228.56 Kb.
ABSTRACT
Organisms have developed systems antioxidant defense
systems to deal with the planet oxidative atmosphere and
with the oxidative metabolism. These systems allowed
evolution of life in this antioxidant defense to confront to
the atmosphere oxidative of the planet and to the oxidative
metabolism that allowed evolution of life in that
atmosphere, reaching efficient buffer antioxidant systems
that conserve capacity to reduce free radicals, reactive
species and endogenous and exogenous oxidants. These
buffer antioxidant systems lead into the system of
glutatión-NADPH and with NADP
+ reduction from the
metabolism, where regenerate and load hydrogens and
electrons.Of such a formantioxidant enzymes, antioxidant
cosustrates and antioxidant endogenous and exogenous
generate barriers to take the reduction of the oxidants and
to diminish thisway their oxidative power,withwhat there
are confront the varieties of diverse species and oxidative
forms capable of attacking to the organism. The
antioxidant systems can measure up of different specific
forms and the global buffer antioxidant system can
measure up to the tests of total antioxidant capacity; the
technical and interpretive improvement of these
technologies allowed to profounder into the basic
knowledge of the forms of defense of the cell, it has
multiplied the studies of antioxidant capacity from pure
substances up to complex organisms, serving even for
diagnostic methods and evaluation of the efficiency of
treatments.
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