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Colegio de Medicina Interna de México.

2012, Number 4

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Med Int Mex 2012; 28 (4)

Unilateral lupus pneumonitis

Carrillo ER, Peña PC

Language: Spanish
References: 40
Page: 374-379
PDF size: 182.30 Kb.


ABSTRACT

Systemic lupus erythematosus (SLE) is an autoimmune disease with a multisystem involvement. Pleuro-pulmonary manifestations are present in almost half of the patients during the disease course and may be the presenting symptoms in 4-5% of patients with SLE. Acute lupus pneumonitis (ALP) is an uncommon manifestation reported to occur in up to 4% of lupus cohorts, in 50% of whom it may be the presenting symptom. Usually, ALP occurs during a generalized lupus flare and occurs in association with multisystem involvement. The clinical presentation is nonspecific with fever, dyspnea, pleuritic chest pain, and cough with minimal sputum production. Histological features of ALP are nonspecific. The differential diagnosis of ALP is broad and includes infection, alveolar hemorrhage, pulmonary embolism, etc. The therapy for ALP is high dose systemic corticosteroids and other immunosuppressive drugs. The aim of this paper is to describe an unusual presentation of ALP characterized by unilateral pulmonary involvement and review literature.


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