2011, Number 4
Rev Mex Med Repro 2011; 3.4 (4)
Determinants on the results of intrauterine insemination: analysis of 1,040 consecutive cycles
González CJ, Linder EC, Aguirre RG,Vilchis NP, Smeke BJ, Navarro MC, Rodríguez MJA
Language: Spanish
References: 10
Page: 193-198
PDF size: 86.18 Kb.
ABSTRACT
Background: There are a variety of infertility treatments, however, intrauterine insemination (IUI) is still useful, when compared with more complex techniques.Objective: To determine factors favoring the reproductive success in patients with diagnosis of infertility who underwent ovulation induction and intrauterine insemination, valuing the success with the percentage of pregnancies with fetal heart rate (+).
Material and method: A retrospective study of 1,040 consecutive cycles of IUI, from January 1998 to December 2004. We included patients undergoing ovulation induction and IUI. We excluded those with incomplete records or who discontinued treatment.
Results: Of 1,040 cycles, pregnancy was achieved in 97 patients. The use of monotherapy for ovulation induction had lower reproductive success. With 4 follicles we obtained a significantly higher proportion of pregnancy, another finding was that patients with higher reproductive success had a higher total numbers of motile sperm post-washing, and we found that the patients with endometriosis had a lower pregnancy rate (31.3% vs 68.6%, p ‹ 0.001).
Conclusions: Intrauterine insemination is a useful, acceptable and accessible technique. The factors favoring the reproductive success are: the use of combined therapy for ovulation induction, the use of 4 follicles, a high number of motile sperm and a etiology of the infertility different from endometriosis.
REFERENCES
Nyboe A, Goossens V, Bhattacharya S, Ferraretti AP, et al. Assisted reproductive technology and intrauterine inseminations in Europe, 2005: results generated from European registers by ESHRE: ESHRE. The European FIV Monitoring Programme (EIM), for the European Society of Human Reproduction and Embryology (ESHRE). Hum Reprod 2009;24(6):1267-1287.