2011, Number 2
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Biotecnol Apl 2011; 28 (2)
Protective immune response against Neisseria meningitidis serogroup B after immunization with peptides mimicking a capsular polysaccharide epitope
Menéndez T, Garay HE, Reyes O, Cruz Y, Coizeau E, Santiago NF, Chinea G, Cobas K, Caballero E, Morera V, Noda J, Carmenate T, Soria Y, Brown E, Martín A, Yero D, González S, Guillén GE
Language: Spanish
References: 15
Page: 113-115
PDF size: 78.08 Kb.
Text Extraction
The Gram-negative bacterium
Neisseria meningitidis is an important cause of meningitis and septicemia worldwide. Meningococcal disease is a life threatening illness that may progress to death even after medical intervention. Approximately 500 000 - 1 000 000 cases of invasive meningococcal disease occur annually worldwide with a 10% mortality rate. Significant sequelae, including neurological damage, limb loss and hearing loss, occur in up to 20% of survivors. Meningococcal disease is more common among infants and young children (1). Prevention through vaccination remains the most effective approach to control invasive meningococcal disease.
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