2000, Number 1
<< Back Next >>
An Med Asoc Med Hosp ABC 2000; 45 (1)
Prevention of infections in arthroplasties and hemiarthroplasties of the hip
Campos ALF, Lazcano MMA
Language: Spanish
References: 23
Page: 27-30
PDF size: 107.21 Kb.
ABSTRACT
Wound contamination may occur in the operating room from 3 sources. 1, airborne particles. 2, particles from the skin of the operating room personal and 3: endogenous infections. Airborne contamination is controlled with clean laminar airflow. Bacterial shedding with impermeable gowns. The endogenous infections with local and systemic antibiotics. In total hip arthroplasty the incidence of infection reported by Nelson is 5.8% without antibiotics and 1.3% with antibiotics, in sterile operating room 0.7% without antibiotics and 0.6% with antibiotics. 1.0% with ultraviolet high and antibiotics. In a previous study 100 operations without clean operating room in total hip arthroplasties we found 4% of infections, and 1% with clean operating room. In the present study with 90 patients with partial and total hip arthroplasties cement with gentamicin was used, as well as collagen with gentamicin we had no deep infections and one superficial 0.9%. In sterile operating room. With the use with collagen and gentamicin, local concentration of the antibiotic is 500 to 100 times superior to the hematic concentration, and prevents infections. It is important to use in patients with renal problems in which systemic antibiotics can not be used.
REFERENCES
Charnley J, Eftekar N. Postoperative infection in total prosthetic replacement arthroplasty of the hip joint: With special reference to the bacterial content of the operating room. British J Surg 1969; 56: 641-649.
Charnley J. Eftekar N. Penetration of gown material by organisms from the surgeons Body. Lancet 1969; 1: 172-174.
Lazcano MA, Frías H, Somellera R, Ovando Rojas E. Implante total de cadera tipo Charnley. Revisión de 100 casos. Acta Ortopédica Latinoamericana 1974; 1 (2): 238-241.
Lazcano MA y Asoc. Control de infecciones en artroplastia total de cadera. Acta Ortopédica Latinoamericana 1978; 5: (2): 103-107.
Charnley J. Low friction arthroplasty of the hip. New York: Springer Verlag, 1980.
Fitzgerald RH Jr, Peterson LA, Washington JA, Coventry MB. Bacterial colonization of wounds and sepsis in total hip arthroplasty. J Bone Joint Surg 1973; 55 (A): 1242-1250.
Salvati E, Robinson RP, Zeno S et al. Infection rates after 3175 total hip and total knee replacements performed with and without horizontal unidirectional filtered air. J Bone Joint Surg 1972; 64 (A): 4.
Nelson P. The operating room environment and its influence in deep wound infections. Proceedings of the Fifth Open Scientific Meeting. Hip Society 1977.
Lidwell OM, Lowbury EJL et al. Infection following orthopaedic surgery in conventional and unidirectional airflow opereting theatres. Br Med J 1982; 285: 10-14.
Boyd JR, Burke JK. A double blind clinical trial of prophylactic antibiotic in hip fracture. J Bone Joint Surg 1973; 55 (A): 1251-1258.
Tachdjian MO, Compere EL. Post-operative wound infection in Orthopaedic surgery: Evaluation of prophylactic antibiotic. J Int Col Surg 1957; 28: 797-805.
Benfer J. Stuck H. Promotion of fracture healing by local collagen application. Dtsch Med Wschr 1972; 97: 523-524.
Colchero F. Tratamiento integral del paciente con infección ósea. México: Editorial Trillas, 1990.
Eckstein T, Steveling H, Buchner E. Initial clinical experience with gentamicin. Deutsche. Zeitschrift for Mund. Kiefer und Gesichts. Chirugie 1989: 13-4.
Eckstein T, Steveling H, Buchwer E. Initial clinical experience with a new collagen sponge coated with gentamicin. Deutsche. Zeitschrift for Mund. Kiefer und Gesichts. Chirugie 1989; 13: 4.
Guzmán Valdivia G, Guerrero MT. Evaluación clínica del implante de colágena. Gentamicina en heridas quirúrgicas sucias. XIV Congreso de la Asociación Mexicana Ortopedia y Traumatología, Mérida, Yuc, 25 de octubre 1997.
Hasselbach Ch. The management of infected THP revisions using gentamicin loaded collagen sponges. 26 World Congress of the International Collage of Surgeons Milan (Italy), 1988; 3-9.
Hasselbach Ch. Clinical treatment and pharmacokinetics of collagen gentamicin as adjuvant local therapy for bone infections. Unfalchirurgie 1989; 92: 459-470.
Ipsen T, Joergensen P et al. Gentamicin Collagen Spongen for local applications. Acta Orth Scand 1991; 62 (6). 592-594.
Kuster H. Bone regeneration after fibrin spongiosa and collagen spongiosa implantation an animal experience comparison. Hckenbroch Refior, Jager Thieme Verlaz Stuggar 1982: 204.
Lutten C, Lorenz H, Thomas H. Replacement operations for hip and knee joint endoprosthesis. Local antibiotic therapy and prophylaxis with an absorbable biological song carrier. Crispraxis 1989; 40: 287-291.
Lazcano Marroquín MA, Suárez V. Colágeno bovino con gentamicina. Experiencia en México. Congreso AMOT XIV, Mérida, Yuc. 25 Octubre 1997.
Craig WA, Legget J, Totsukat, Volgenman B. Key pharmacokinetic parameters of antibiotic efficacy in experimental animal infection. J Drug Dev 1988; 1(53): 7-15.